依曲替酯结构式
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常用名 | 依曲替酯 | 英文名 | Etretinate |
|---|---|---|---|---|
| CAS号 | 54350-48-0 | 分子量 | 354.483 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 506.4±38.0 °C at 760 mmHg | |
| 分子式 | C23H30O3 | 熔点 | 104-105ºC | |
| MSDS | N/A | 闪点 | 219.4±21.4 °C |
依曲替酯用途【用途一】 用于治疗严重的牛皮癣、红斑性角化症等 |
| 中文名 | 依曲替酯 |
|---|---|
| 英文名 | etretinate |
| 中文别名 | 替维甲 | 阿维A酯 | 全反式-9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-壬四烯酸乙酯 |
| 英文别名 | 更多 |
| 密度 | 1.0±0.1 g/cm3 |
|---|---|
| 沸点 | 506.4±38.0 °C at 760 mmHg |
| 熔点 | 104-105ºC |
| 分子式 | C23H30O3 |
| 分子量 | 354.483 |
| 闪点 | 219.4±21.4 °C |
| 精确质量 | 354.219482 |
| PSA | 35.53000 |
| LogP | 6.77 |
| 外观性状 | 结晶固体 |
| 蒸汽压 | 0.0±1.3 mmHg at 25°C |
| 折射率 | 1.544 |
| 储存条件 | Amber Vial, -20°C Freezer |
| 危害码 (欧洲) | Xn |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
| 依曲替酯上游产品 3 | |
|---|---|
| 依曲替酯下游产品 0 | |
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Systemic retinoids in the management of ichthyoses and related skin types.
Dermatol. Ther. 26(1) , 26-38, (2013) The term retinoid includes both natural and synthetic derivatives of vitamin A. Retinoid-containing treatments have been used since ~1550BC by the early Egyptians. Treatment of ichthyosiform disorders... |
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The effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs.
Expert Opin. Drug Metab. Toxicol. 8(8) , 959-72, (2012) Alcohol has long been suspected to be a triggering and precipitating factor of psoriasis. Alcohol misuse is common in patients with moderate-to-severe psoriasis and appears to impair treatment outcome... |
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Generalized pustular psoriasis in a child: observation of long-term combination therapy with etretinate and calcipotriol for 16 years.
Pediatr. Dermatol. 29(2) , 206-8, (2012) Generalized pustular psoriasis (GPP) is a rare condition in young children. It is difficult to treat and may require long-term systemic therapy. We report the long-term course of a 3-year-old boy whos... |
| ethyl (all-E)-9-(4-methyoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate |
| 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester |
| Retinoid |
| 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester |
| Ethyl etrinoate |
| Ro 10-9359 |
| Etretinatum [INN-Latin] |
| Etretinato |
| ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate |
| Etretinatum |
| ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate |
| EINECS 259-119-3 |
| MFCD00866624 |
| Ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate |
| Etretinato [INN-Spanish] |
| Tegison |