依曲替酯

• 常用名: 依曲替酯
• 英文名: Etretinate
• CAS号: 54350-48-0
• 分子量: 354.483
• 密度: 1.0±0.1 g/cm3
• 沸点: 506.4±38.0 °C at 760 mmHg
• 分子式: C₂₃H₃₀O₃
• 熔点: 104-105ºC
• 闪点: 219.4±21.4 °C

依曲替酯用途

Etretinate(Ro 10-9359)是一用于治疗银屑病的药物,临床上已被acitretin取代使用。

依曲替酯名称

• 中文名: 依曲替酯
• 英文名: etretinate
• 中文别名: 替维甲 | 阿维A酯 | 全反式-9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-壬四烯酸乙酯

依曲替酯生物活性

• 描述: Etretinate(Ro 10-9359)是一用于治疗银屑病的药物,临床上已被acitretin取代使用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他

依曲替酯物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 506.4±38.0 °C at 760 mmHg
• 熔点: 104-105ºC
• 分子式: C₂₃H₃₀O₃
• 分子量: 354.483
• 闪点: 219.4±21.4 °C
• 精确质量: 354.219482
• PSA: 35.53000
• LogP: 6.77
• InChIKey: HQMNCQVAMBCHCO-DJRRULDNSA-N
• SMILES: CCOC(=O)C=C(C)C=CC=C(C)C=Cc1c(C)cc(OC)c(C)c1C
• 外观性状: 结晶固体
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.544
• 储存条件: Amber Vial, -20°C Freezer

依曲替酯毒性和生态

依曲替酯安全信息

• 危害码 (欧洲): Xn
• 危险品运输编码: NONH for all modes of transport

依曲替酯靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：Hypervitaminosis dose determined as a measure of toxicity 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL737532

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：Therapeutic index calculated as the ratio of hypervitaminosis A dose to the ED50 dose 来源：ChEMBL 靶标：N/A External Id：CHEMBL850453

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green ... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_green

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio ... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_ratio

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue c... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_blue

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依曲替酯英文别名

• ethyl (all-E)-9-(4-methyoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
• 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester
• Retinoid
• 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester
• Ethyl etrinoate
• Ro 10-9359
• Etretinatum [INN-Latin]
• Etretinato
• ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
• Etretinatum
• ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
• EINECS 259-119-3
• MFCD00866624
• Ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
• Etretinato [INN-Spanish]
• Tegison