Atherosperminine

• 常用名: Atherosperminine
• 英文名: Atherosperminine
• CAS号: 5531-98-6
• 分子量: 309.40200
• 密度: 1.109g/cm3
• 沸点: 466.1ºC at 760mmHg
• 分子式: C₂₀H₂₃NO₂
• 熔点: N/A
• 闪点: 161.5ºC

Atherosperminine用途

Atherosperminine (Atherospermine) 是一种天然的生物碱。Atherosperminine 在体外表现出抗疟原虫活性,其 IC50 值为 5.80 μM。Atherosperminine 是一种良好的还原剂,具有螯合金属的能力,具有促氧化活性。Atherosperminine 对气管有非特异性的弛缓作用。

Atherosperminine名称

• 中文名: 芒籽宁
• 英文名: Atherosperminine

Atherosperminine生物活性

• 描述: Atherosperminine (Atherospermine) 是一种天然的生物碱。Atherosperminine 在体外表现出抗疟原虫活性,其 IC50 值为 5.80 μM。Atherosperminine 是一种良好的还原剂,具有螯合金属的能力,具有促氧化活性。Atherosperminine 对气管有非特异性的弛缓作用。
• 相关类别:
  研究领域 >> 感染
• 靶点实验:

  IC50: 5.80 μM (P. falciparum, K1 strain)[1]

• 参考文献:

  [1]. Ayu Afiqah Nasrullah, et al. Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae). Molecules. 2013 Jul; 18(7): 8009–8017.

  [2]. C H Lin, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma. Eur J Pharmacol. 1993 Jun 11;237(1):109-16.

Atherosperminine物理化学性质

• 密度: 1.109g/cm3
• 沸点: 466.1ºC at 760mmHg
• 分子式: C₂₀H₂₃NO₂
• 分子量: 309.40200
• 闪点: 161.5ºC
• 精确质量: 309.17300
• PSA: 21.70000
• LogP: 4.11430
• InChIKey: UZZFAUDNCIFFPM-UHFFFAOYSA-N
• SMILES: COc1cc(CCN(C)C)c2ccc3ccccc3c2c1OC
• 储存条件: 2-8℃

Atherosperminine安全信息

• 海关编码: 2922199090

Atherosperminine海关

• 海关编码: 2922199090
• 中文概述: 2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
• Summary: 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Atherosperminine靶点实验

查看更多实验

实验名称：Selectivity ratio of Ki for D1 receptor of Wistar rat striatal membranes to Ki for D2... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2416962

实验名称：Inhibition of equine serum BChE at 100 ug/ml preincubated for 15 mins followed by add... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL3828921

实验名称：Inhibition of electric eel AChE preincubated for 15 mins followed by addition of acet... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL3828922

实验名称：Inhibition of equine serum BChE preincubated for 15 mins followed by addition of S-bu... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL3829309

实验名称：Inhibition of electric eel AChE at 100 ug/ml preincubated for 15 mins followed by add... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL3828920

共5条，当前第1页，共1页

1

Atherosperminine英文别名

• 3,4-Dimethoxy-N,N-dimethyl-1-phenanthreneethanamine
• [2-(3,4-dimethoxy-[1]phenanthryl)-ethyl]-dimethyl-amine
• O-methylargentinine
• [2-(3,4-Dimethoxy-[1]phenanthryl)-aethyl]-dimethyl-amin
• 1-[2-(N,N-dimethylaminoethyl)]-3,4-dimethoxyphenanthrene
• phenanthrenes atherosperminine
• atherospermine
• N,N-Dimethyl-3,4-dimethoxyphenanthrene-1-ethanamine