Flavanomarein

• 常用名: Flavanomarein
• 英文名: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
• CAS号: 577-38-8
• 分子量: 450.39300
• 密度: 1.665g/cm3
• 沸点: 818.2ºC at 760 mmHg
• 分子式: C₂₁H₂₂O₁₁
• 熔点: 243-246ºC
• 闪点: 288.9ºC

Flavanomarein用途

Flavanomarein 是 Coreopsis tinctoria Nutt 的主要黄酮类化合物,对糖尿病性肾病具有保护作用。Flavanomarein 具有良好的抗氧化,降糖,降压和降血脂活性。

Flavanomarein名称

• 中文名: 黄诺马苷
• 英文名: flavanomarein

Flavanomarein生物活性

• 描述: Flavanomarein 是 Coreopsis tinctoria Nutt 的主要黄酮类化合物,对糖尿病性肾病具有保护作用。Flavanomarein 具有良好的抗氧化,降糖,降压和降血脂活性。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10(1):439.

  [2]. Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204.

Flavanomarein物理化学性质

• 密度: 1.665g/cm3
• 沸点: 818.2ºC at 760 mmHg
• 熔点: 243-246ºC
• 分子式: C₂₁H₂₂O₁₁
• 分子量: 450.39300
• 闪点: 288.9ºC
• 精确质量: 450.11600
• PSA: 186.37000
• InChIKey: DGGOLFCPSUVVHX-RTHJTPBESA-N
• SMILES: O=C1CC(c2ccc(O)c(O)c2)Oc2c1ccc(OC1OC(CO)C(O)C(O)C1O)c2O
• 折射率: 1.712
• 储存条件: 室温

Flavanomarein安全信息

• 危害码 (欧洲): Xi

Flavanomarein靶点实验

查看更多实验

实验名称：Inhibition of electric eel AChE at 2 mg/ml by Ellman's method 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL2166270

实验名称：Inhibition of horse BChE at 2 mg/ml by Ellman's method 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL2166271

实验名称：Cytotoxicity against human HL cells assessed as cell viability at 50 uM after 72 hrs ... 来源：ChEMBL 靶标：HL External Id：CHEMBL4135472

实验名称：Antichlamydial activity against Chlamydia pneumoniae K7 infected in HL cells assessed... 来源：ChEMBL 靶标：Chlamydia pneumoniae External Id：CHEMBL4135473

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of binding or entry into cells for Marburg Virus 来源：NCGC 靶标：gene 4 small orf - Marburg virus External Id：VSVM-OFFLINE

实验名称：qHTS for Inhibitors of binding or entry into cells for Lassa Virus 来源：NCGC 靶标：N/A External Id：VSVL-OFFLINE

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Flavanomarein英文别名

• isookanin-7-o-glucoside
• 7-o-glucosyl-4',5',8-trihydroxyflavanone
• isookanin-7-glucoside
• 3',4',7,8-tetrahydroxyflavanone-7-o-glucoside
• trihydroxyflavanone