C-7280948

• 常用名: C-7280948
• 英文名: C7280948
• CAS号: 587850-67-7
• 分子量: 276.354
• 密度: 1.3±0.1 g/cm3
• 沸点: 481.1±55.0 °C at 760 mmHg
• 分子式: C₁₄H₁₆N₂O₂S
• 熔点: N/A
• 闪点: 244.8±31.5 °C

C-7280948用途

C-7280948是PRMT1抑制剂。

C-7280948名称

• 中文名: 4-氨基-N-(2-苯基乙基)苯磺酰胺
• 英文名: 4-amino-N-(2-phenylethyl)benzenesulfonamide

C-7280948生物活性

• 描述: C-7280948是PRMT1抑制剂。
• 相关类别:
  信号通路 >> 表观遗传学 >> 组蛋白甲基转移酶
  研究领域 >> 其他
• 参考文献:

  [1]. Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011 Jun 15;19(12):3717-3731.

C-7280948物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 481.1±55.0 °C at 760 mmHg
• 分子式: C₁₄H₁₆N₂O₂S
• 分子量: 276.354
• 闪点: 244.8±31.5 °C
• 精确质量: 276.093262
• PSA: 80.57000
• LogP: 2.18
• InChIKey: BYWZPUPRVIECEC-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)NCCc2ccccc2)cc1
• 外观性状: white solid
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.617
• 储存条件: -20℃

C-7280948安全信息

• 海关编码: 2935009090

C-7280948海关

• 海关编码: 2935009090
• 中文概述: 2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

C-7280948靶点实验

查看更多实验

实验名称：Cytotoxicity against human MOLT3 cells after 48 hrs by XTT assay 来源：ChEMBL 靶标：MOLT-3 External Id：CHEMBL2432320

实验名称：Inhibition of human recombinant PRMT1-mediated arginine methylation using nonhistone ... 来源：ChEMBL 靶标：Protein arginine N-methyltransferase 1 External Id：CHEMBL1799390

实验名称：qHTS screening for TAG (triacylglycerol) accumulators in algae 来源：11812 靶标：N/A External Id：FATTTLab-Algae-Lipid

实验名称：Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in E... 来源：ChEMBL 靶标：Protein arginine N-methyltransferase 1 External Id：CHEMBL1273382

实验名称：Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherich... 来源：ChEMBL 靶标：Protein arginine N-methyltransferase 1 External Id：CHEMBL1273385

实验名称：Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL2432323

实验名称：Cytotoxicity against human HuCCa1 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2432322

实验名称：Cytotoxicity against human A549 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL2432321

实验名称：Alphascreen assay for small molecules abrogating mHTT-CaM Interaction 来源：24983 靶标：Huntingtin External Id：KUHTS-Muma KU-CaM-Htt INH-01

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

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C-7280948英文别名

• sulfanilic acid phenethylamide
• Sulfanilsaeure-phenaethylamid
• 4-amino-N-phenethylbenzenesulfonamide
• 4-Amino-N-(2-phenylethyl)benzenesulfonamide
• C7280948
• C-7280948