[TYR11] SOMATOSTATIN

• 常用名: [TYR11] SOMATOSTATIN
• 英文名: [Tyr11]-Somatostatin
• CAS号: 59481-27-5
• 分子量: 1653.878
• 密度: 1.5±0.1 g/cm3
• 沸点: 2000.6±65.0 °C at 760 mmHg
• 分子式: C₇₆H₁₀₄N₁₈O₂₀S₂
• 熔点: N/A
• 闪点: 1163.7±34.3 °C

[TYR11] SOMATOSTATIN用途

[Tyr11]-Somatostatin 是一种用于蛋白质组学研究的神经活性肽。Somatostatin 是影响视网膜生理的多种神经活性物质之一。

[TYR11] SOMATOSTATIN名称

• 中文名: [TYR11] SOMATOSTATIN
• 英文名: L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide

[TYR11] SOMATOSTATIN生物活性

• 描述: [Tyr11]-Somatostatin 是一种用于蛋白质组学研究的神经活性肽。Somatostatin 是影响视网膜生理的多种神经活性物质之一。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 体外研究: 碘化[Tyr11]-生长抑素产生GH4C1垂体细胞中生长抑素受体的超高亲和力配体[2]。
• 参考文献:

  [1]. Vasilaki A, et al. Somatostatin mediates nitric oxide production by activating sst(2) receptors in the rat retina. Neuropharmacology. 2002;43(5):899-909.

  [2]. Presky DH, Schonbrunn A. Iodination of [Tyr11]somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells. Mol Pharmacol. 1988;34(5):651-658.

[TYR11] SOMATOSTATIN物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 2000.6±65.0 °C at 760 mmHg
• 分子式: C₇₆H₁₀₄N₁₈O₂₀S₂
• 分子量: 1653.878
• 闪点: 1163.7±34.3 °C
• 精确质量: 1652.711548
• PSA: 684.06000
• LogP: -4.99
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.676

[TYR11] SOMATOSTATIN英文别名

• Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys
• L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
• Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-13-[(4-hydroxyphenyl)methyl]-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-25,28-bis(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-
• (Tyr11)-Somatostatin-14