[Tyr11]-Somatostatin

Modify Date: 2024-01-02 15:37:58

[Tyr11]-Somatostatin Structure
[Tyr11]-Somatostatin structure
Common Name [Tyr11]-Somatostatin
CAS Number 59481-27-5 Molecular Weight 1653.878
Density 1.5±0.1 g/cm3 Boiling Point 2000.6±65.0 °C at 760 mmHg
Molecular Formula C76H104N18O20S2 Melting Point N/A
MSDS N/A Flash Point 1163.7±34.3 °C

 Use of [Tyr11]-Somatostatin


[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1].

 Names

Name L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
Synonym More Synonyms

 [Tyr11]-Somatostatin Biological Activity

Description [Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1].
Related Catalog
In Vitro Iodination of [Tyr11]-Somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells[2].
References

[1]. Vasilaki A, et al. Somatostatin mediates nitric oxide production by activating sst(2) receptors in the rat retina. Neuropharmacology. 2002;43(5):899-909.

[2]. Presky DH, Schonbrunn A. Iodination of [Tyr11]somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells. Mol Pharmacol. 1988;34(5):651-658.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 2000.6±65.0 °C at 760 mmHg
Molecular Formula C76H104N18O20S2
Molecular Weight 1653.878
Flash Point 1163.7±34.3 °C
Exact Mass 1652.711548
PSA 684.06000
LogP -4.99
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.676

 Synonyms

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys
L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-25,28-dibenzyl-4-carboxy-13-(4-hydroxybenzyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-13-[(4-hydroxyphenyl)methyl]-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-25,28-bis(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-
(Tyr11)-Somatostatin-14
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