5-邻氟基苯基-2-氨基-1,3,4-噻二唑

• 常用名: 5-邻氟基苯基-2-氨基-1,3,4-噻二唑
• 英文名: 5-(2-Fluoro-phenyl)-[1,3,4]thiadiazol-2-ylamine
• CAS号: 59565-51-4
• 分子量: 195.22
• 密度: 1.423g/cm3
• 沸点: 360.5ºC at 760 mmHg
• 分子式: C₈H₆FN₃S
• 熔点: N/A
• 闪点: 171.8ºC

5-邻氟基苯基-2-氨基-1,3,4-噻二唑用途

Anticonvulsant agent 3 是一种 2-氨基衍生物,具有 抗惊厥活性。

5-邻氟基苯基-2-氨基-1,3,4-噻二唑名称

• 中文名: 5-邻氟基苯基-2-氨基-1,3,4-噻二唑
• 英文名: 5-(2-fluorophenyl)-1,3,4-thiadiazol-2-amine
• 中文别名: 2-氨基-5-(2-氟苯基)-1,3,4-噻二唑

5-邻氟基苯基-2-氨基-1,3,4-噻二唑生物活性

• 描述: Anticonvulsant agent 3 是一种 2-氨基衍生物,具有 抗惊厥活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. A. FOROUMADI, et al. Synthesis and Anticonvulsant Activity of 5-Aryl-l,3,4-thiadiazole Derivatives. Pharmacy and Pharmacology CommunicationsVolume 6, Issue 1 p. 31-33

5-邻氟基苯基-2-氨基-1,3,4-噻二唑物理化学性质

• 密度: 1.423g/cm3
• 沸点: 360.5ºC at 760 mmHg
• 分子式: C₈H₆FN₃S
• 分子量: 195.22
• 闪点: 171.8ºC
• 精确质量: 195.02700
• PSA: 80.04000
• LogP: 2.50760
• InChIKey: COIYYVXYSKVNIO-UHFFFAOYSA-N
• SMILES: Nc1nnc(-c2ccccc2F)s1
• 外观性状: 白色至灰白色固体
• 折射率: 1.643
• 储存条件: 2-8°C， 避光

5-邻氟基苯基-2-氨基-1,3,4-噻二唑安全信息

• 危害码 (欧洲): Xn

5-邻氟基苯基-2-氨基-1,3,4-噻二唑靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

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实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen 来源：NCGC External Id：tdp43-p2-repeat

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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5-邻氟基苯基-2-氨基-1,3,4-噻二唑英文别名

• 2-Amino-5-(2-fluorophenyl)-1,3,4-thiadiazole
• 5-(2-fluorophenyl)-1,3,4-thiadiazole-2-ylamine
• 5-(2-Fluoro-phenyl)-[1,3,4]thiadiazol-2-ylamine
• 2-Amino-5-o-fluorphenyl-1,3,4-thiadiazol