吡酮洛芬

• 常用名: 吡酮洛芬
• 英文名: Piketoprofen
• CAS号: 60576-13-8
• 分子量: 344.41
• 密度: 1.195g/cm3
• 沸点: 583.5ºC at 760 mmHg
• 分子式: C₂₂H₂₀N₂O₂
• 熔点: N/A
• 闪点: 306.7ºC

吡酮洛芬用途

吡酮洛芬是一种非甾体抗炎剂,可作为研究软组织风湿病的乳膏制剂[1]。

吡酮洛芬名称

• 中文名: 吡酮洛芬
• 英文名: 2-(3-benzoylphenyl)-N-(4-methylpyridin-2-yl)propanamide

吡酮洛芬生物活性

• 描述: 吡酮洛芬是一种非甾体抗炎剂,可作为研究软组织风湿病的乳膏制剂[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Burgos A, et al. Double-blind, double-dummy comparative study of local action transcutaneous flurbiprofen (flurbiprofen LAT) versus piketoprofen cream in the treatment of extra-articular rheumatism[J]. Clinical Drug Investigation, 2001, 21: 95-102.

吡酮洛芬物理化学性质

• 密度: 1.195g/cm3
• 沸点: 583.5ºC at 760 mmHg
• 分子式: C₂₂H₂₀N₂O₂
• 分子量: 344.41
• 闪点: 306.7ºC
• 精确质量: 344.15200
• PSA: 59.06000
• LogP: 4.43620
• InChIKey: ASFKKFRSMGBFRO-UHFFFAOYSA-N
• SMILES: Cc1ccnc(NC(=O)C(C)c2cccc(C(=O)c3ccccc3)c2)c1
• 折射率: 1.628

吡酮洛芬靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Antiviral activity against SARS-CoV-2 (USA-WA1/2020 strain) measured by imaging in HR... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303810

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

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吡酮洛芬英文别名

• Piketoprofeno
• Calmatel (TN)
• Piketoprofen
• Piketoprofene
• Piketoprofenum
• 2-(3-benzoylphenyl)-n-(4-methyl-2-pyridyl)propionamide
• Piketoprofen (INN)