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ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate

更新时间:2025-09-18 11:54:53

ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate结构式
ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate结构式
委托求购
常用名 ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate 英文名 ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS号 6069-01-8 分子量 540.93900
密度 1.435g/cm3 沸点 531.4ºC at 760 mmHg
分子式 C24H20ClF3N2O5S 熔点 N/A
MSDS N/A 闪点 275.2ºC

 名称

英文名 ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
英文别名 更多

 物理化学性质

密度 1.435g/cm3
沸点 531.4ºC at 760 mmHg
分子式 C24H20ClF3N2O5S
分子量 540.93900
闪点 275.2ºC
精确质量 540.07300
PSA 125.46000
LogP 6.87560
InChIKey SAGOXOOZDUQAAT-UHFFFAOYSA-N
SMILES CCOC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)c1C
折射率 1.615

 合成线路

~%

ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate结构式

ethyl 5-[[2-chl...

6069-01-8

文献:Abramow; Maikowa Trudy Kazansk.chim.technol.Inst.Chem.Abstr., 1959 , # 26 p. 104,106 Trudy Kazansk.chim.technol.Inst.Chem.Abstr., 1960 , p. 24340

~90%

ethyl 5-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoyl]-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate结构式

ethyl 5-[[2-chl...

6069-01-8

文献:Bettermann, Gerhard; Schomburg, Dietmar; Schmutzler, Reinhard Phosphorus and Sulfur and the Related Elements, 1986 , vol. 28, p. 327 - 336

 靶点实验

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实验名称:Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridg...
来源:1102
靶标:N/A
External Id:20130627FPNS3INTERFERECB
实验名称:Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:HCMV UL50
External Id:HMS1262
实验名称:Fluorescence polarization based primary biochemical high throughput screening assay o...
来源:1102
靶标:NS3 [Hepatitis C virus]
External Id:20130624FPNS3DACB
实验名称:High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS1303
实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
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 英文别名

phosphorodichloridous acid 2-methoxy-ethyl ester
(2-methoxyethoxy)dichlorophosphine
HMS598C08
Dichlorophosphorigsaeure-(2-methoxy-aethylester)
ETHYL 5-[[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL]-2-[(4-METHOXYBENZOYL)AMINO]-4-METHYL-THIOPHENE-3-CARBOXYLATE
2-Methoxyethyl-1-dichlorphosphit
Dichlor-<2-methoxy-aethyl>-phosphit
dichlorophosphoric acid-(2-methoxy-ethyl ester)
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