methyl piperate

• 常用名: methyl piperate
• 英文名: methyl piperate
• CAS号: 6190-46-1
• 分子量: 232.23
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₂O₄
• 熔点: N/A
• 闪点: N/A

methyl piperate用途

Methylpiperate 是一种胡椒碱类生物碱,具有显著的 MAO 抑制活性 (IC50 3.6 μM) 。Methylpiperate 对 MAO-B (IC50 1.6 μM) 比 MAO-A (IC50 27.1 μM) 有选择性抑制作用。Methylpiperate 可用于治疗精神障碍。

methyl piperate名称

• 英文名: methyl piperate

methyl piperate生物活性

• 描述: Methylpiperate 是一种胡椒碱类生物碱,具有显著的 MAO 抑制活性 (IC50 3.6 μM) 。Methylpiperate 对 MAO-B (IC50 1.6 μM) 比 MAO-A (IC50 27.1 μM) 有选择性抑制作用。Methylpiperate 可用于治疗精神障碍。
• 相关类别:
  信号通路 >> 神经信号通路 >> 单胺氧化酶
  研究领域 >> 神经疾病
• 靶点实验:

  MAO-B

• 参考文献:

  [1]. Lee SA, et al. Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase. Arch Pharm Res. 2008 Jun;31(6):679-83.

methyl piperate物理化学性质

• 分子式: C₁₃H₁₂O₄
• 分子量: 232.23
• 精确质量: 232.07400
• PSA: 44.76000
• LogP: 2.15770
• InChIKey: VOZJBFJHMHRLDN-ZUVMSYQZSA-N
• SMILES: COC(=O)C=CC=Cc1ccc2c(c1)OCO2

methyl piperate靶点实验

查看更多实验

实验名称：Inhibition of D-galactosamine/TNFalpha-induced cell death in ddY mouse hepatocytes at... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL950306

实验名称：Inhibition of D-galactosamine/TNFalpha-induced cell death in ddY mouse hepatocytes at... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL950307

实验名称：Inhibition of D-galactosamine/TNFalpha-induced cell death in ddY mouse hepatocytes at... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL950305

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046861

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046862

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046859

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046860

实验名称：Hepatoprotective activity in ddY mouse peritoneal macrophages assessed as inhibition ... 来源：ChEMBL 靶标：Peritoneal macrophage cell External Id：CHEMBL1046870

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046867

实验名称：Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galact... 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL1046865

共31条，当前第1页，共4页

1

2

3

4