Benzo[b]thiophene-2-carboxamide,N-phenyl

• 常用名: Benzo[b]thiophene-2-carboxamide,N-phenyl
• 英文名: Benzo[b]thiophene-2-carboxamide,N-phenyl
• CAS号: 6314-40-5
• 分子量: 253.31900
• 密度: 1.32g/cm3
• 沸点: 346.2ºC at 760 mmHg
• 分子式: C₁₅H₁₁NOS
• 熔点: N/A
• 闪点: 163.1ºC

用途

Aβ42 agonist-2 (compound 7b) 是能够促进 Aβ42 聚集的小分子化合物。Aβ42 agonist-2 可以与 Aβ42 寡聚体和五聚体相互作用,促进无毒聚集体自组装和快速原纤维形成。Aβ42 agonist-2 可防止 Aβ42 诱导的对 HT22 海马神经元细胞的细胞毒性。

Benzo[b]thiophene-2-carboxamide,N-phenyl名称

• 英文名: N-phenyl-1-benzothiophene-2-carboxamide

Benzo[b]thiophene-2-carboxamide,N-phenyl生物活性

• 描述: Aβ42 agonist-2 (compound 7b) 是能够促进 Aβ42 聚集的小分子化合物。Aβ42 agonist-2 可以与 Aβ42 寡聚体和五聚体相互作用,促进无毒聚集体自组装和快速原纤维形成。Aβ42 agonist-2 可防止 Aβ42 诱导的对 HT22 海马神经元细胞的细胞毒性。
• 相关类别:
  研究领域 >> 神经疾病
• 靶点实验:

  Aβ42 aggregation[1]

• 参考文献:

  [1]. Zhao Y et al. Small Molecules N-Phenylbenzofuran-2-carboxamide and N-Phenylbenzo[b]thiophene-2-carboxamide Promote Beta-Amyloid (Aβ42) Aggregation and Mitigate Neurotoxicity. ACS Chem Neurosci. 2023 Nov 16.

Benzo[b]thiophene-2-carboxamide,N-phenyl物理化学性质

• 密度: 1.32g/cm3
• 沸点: 346.2ºC at 760 mmHg
• 分子式: C₁₅H₁₁NOS
• 分子量: 253.31900
• 闪点: 163.1ºC
• 精确质量: 253.05600
• PSA: 57.34000
• LogP: 4.22660
• InChIKey: QFWHYKVMOFOKHM-UHFFFAOYSA-N
• SMILES: O=C(Nc1ccccc1)c1cc2ccccc2s1
• 折射率: 1.735

Benzo[b]thiophene-2-carboxamide,N-phenyl安全信息

• 海关编码: 2934999090

Benzo[b]thiophene-2-carboxamide,N-phenyl海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Benzo[b]thiophene-2-carboxamide,N-phenyl靶点实验

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Benzo[b]thiophene-2-carboxamide,N-phenyl英文别名

• benzo[b]thiophene-2-carboxylic acid anilide
• benzothiophene-2-carboxanilide
• HMS3078J06
• Benzo[b]thiophen-2-carbonsaeure-anilid
• Benzo[b]thiophene-2-carboxanilide
• 2-Benzo<b>thenoyl-anilid
• N-phenylbenzo[b]thiophene-2-carboxamide