苯甲酰新乌头原碱

• 常用名: 苯甲酰新乌头原碱
• 英文名: Benzoylmesaconine
• CAS号: 63238-67-5
• 分子量: 589.674
• 密度: 1.4±0.1 g/cm3
• 沸点: 703.2±60.0 °C at 760 mmHg
• 分子式: C₃₁H₄₃NO₁₀
• 熔点: N/A
• 闪点: 379.1±32.9 °C

苯甲酰新乌头原碱用途

Benzoylmesaconine是乌头汤最丰富的组分,乌头汤对类风湿性关节炎的治疗效果在中国广泛使用。

苯甲酰新乌头原碱名称

• 中文名: 苯甲酰新乌头原碱
• 英文名: Benzoylmesaconine

苯甲酰新乌头原碱生物活性

• 描述: Benzoylmesaconine是乌头汤最丰富的组分,乌头汤对类风湿性关节炎的治疗效果在中国广泛使用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  天然产物 >> 生物碱
  研究领域 >> 其他
• 参考文献:

  [1]. Dai PM, et al. Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction. Molecules. 2014 Oct 17;19(10):16757-69.

  [2]. Ye L, et al. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med. 2013;2013:941093.

苯甲酰新乌头原碱物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 703.2±60.0 °C at 760 mmHg
• 分子式: C₃₁H₄₃NO₁₀
• 分子量: 589.674
• 闪点: 379.1±32.9 °C
• 精确质量: 589.288696
• PSA: 147.38000
• LogP: 0.37
• InChIKey: PULWZCUZNRVAHT-UHFFFAOYSA-N
• SMILES: COCC12CN(C)C3C4C(OC)C1C3(C(OC)CC2O)C1CC2(O)C(OC)C(O)C4(O)C1C2OC(=O)c1ccccc1
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.637
• 储存条件: 2~8℃

苯甲酰新乌头原碱毒性和生态

苯甲酰新乌头原碱安全信息

• 危害码 (欧洲): Xi

苯甲酰新乌头原碱靶点实验

查看更多实验

实验名称：Cytotoxicity against human HCT8 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：HCT-8 External Id：CHEMBL2067699

实验名称：Antiinflammatory activity in mouse peritoneal macrophages assessed as inhibition of n... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL2067693

实验名称：Cytotoxicity against human BGC823 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：BGC-823 External Id：CHEMBL2067694

实验名称：Antioxidant activity in rat liver microsome assessed as inhibition of FeSO4-induced l... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2067691

实验名称：Hepatoprotective activity against DL-galactosamine-induced cell death in rat WB-F344 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2067692

实验名称：Cytotoxicity against human Ketr3 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：KETR3 External Id：CHEMBL2067697

实验名称：Cytotoxicity against human Bel7402 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：Bel-7402 External Id：CHEMBL2067698

实验名称：Cytotoxicity against human A549 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL2067695

实验名称：Cytotoxicity against human MCF7 cells at 10 uM after 96 hrs by MTT assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL2067696

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苯甲酰新乌头原碱英文别名

• Benzoylmesaconitine
• (1α,3α,6α,14α,15α,16β)-3,8,13,15-Tetrahydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-20-methylaconitan-14-yl benzoate
• O8-Deacetylmesaconitine
• Mesaconine 14-benzoate
• 8-Deacetylmesaconitine
• Benzoylmesaconine