6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮

• 常用名: 6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮
• 英文名: Benzylthiouracil
• CAS号: 6336-50-1
• 分子量: 218.27500
• 密度: 1.32g/cm3
• 沸点: 438.1ºC at 760 mmHg
• 分子式: C₁₁H₁₀N₂OS
• 熔点: N/A
• 闪点: 218.8ºC

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮用途

苄基硫氧嘧啶是一种抗甲状腺机能亢进的活性药物成分[1]。

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮名称

• 中文名: 6-苄基-2-硫脲嘧啶
• 英文名: 6-benzyl-2-sulfanylidene-1H-pyrimidin-4-one

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮生物活性

• 描述: 苄基硫氧嘧啶是一种抗甲状腺机能亢进的活性药物成分[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Rietveld IB, et al. Polymorphism of benzylthiouracil, an active pharmaceutical ingredient against hyperthyroidism. Int J Pharm. 2021;598:120378.

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮物理化学性质

• 密度: 1.32g/cm3
• 沸点: 438.1ºC at 760 mmHg
• 分子式: C₁₁H₁₀N₂OS
• 分子量: 218.27500
• 闪点: 218.8ºC
• 精确质量: 218.05100
• PSA: 80.74000
• LogP: 2.02330
• InChIKey: PNXBXCRWXNESOV-UHFFFAOYSA-N
• SMILES: O=c1cc(Cc2ccccc2)[nH]c(=S)[nH]1
• 折射率: 1.678
• 储存条件: -20°C

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮MSDS

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮MSDS英文版

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮安全信息

• 安全声明 (欧洲): S22-S24/25
• 海关编码: 2933599090

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮海关

• 海关编码: 2933599090
• 中文概述: 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

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实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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6-苄基-2-硫代-2,3-二氢嘧啶-4(1H)-酮英文别名

• Basdene
• 6-benzyl-2-thiouracil
• 6-benzyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• Benzylthiouracil
• 6-benzyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
• 3,4-dihydro-6-phenylmethyl-2-thioxopyrimidin-4(3H)-one
• 6-benzyl thiouracil