Microhelenin C

• 常用名: Microhelenin C
• 英文名: Microhelenin C
• CAS号: 63569-07-3
• 分子量: 346.41700
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₆O₅
• 熔点: N/A
• 闪点: N/A

Microhelenin C用途

Microhelenin C 是一种从 Helenium microcephalum 中提取的倍半萜内酯,具有抗肿瘤活性。

Microhelenin C名称

• 中文名: 小堆心菊素C
• 英文名: [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] (E)-2-methylbut-2-enoate

Microhelenin C生物活性

• 描述: Microhelenin C 是一种从 Helenium microcephalum 中提取的倍半萜内酯,具有抗肿瘤活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Y Imakura, et al. Antitumor agents XXXVI: Structural elucidation of sesquiterpene lactones microhelenins-A, B, and C, microlenin acetate, and plenolin from Helenium microcephalum. J Pharm Sci. 1980 Sep;69(9):1044-9.

Microhelenin C物理化学性质

• 分子式: C₂₀H₂₆O₅
• 分子量: 346.41700
• 精确质量: 346.17800
• PSA: 69.67000
• LogP: 2.84330
• InChIKey: KUPPZVXLWANEJJ-YFVRYKHXSA-N
• SMILES: CC=C(C)C(=O)OC1C2C(CC(C)C3C=CC(=O)C31C)OC(=O)C2C
• 储存条件: 室温

Microhelenin C靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse cloned EN2 cells after 2 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1000733

实验名称：Cytotoxicity against mouse cloned EN2 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1000734

实验名称：Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubat... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4815370

实验名称：Inhibition of NF-kappaB DNA binding by EMSA 来源：ChEMBL 靶标：Transcription factor p65 External Id：CHEMBL861583

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4815373

实验名称：Concentration required for complete inhibition of Nuclear factor kappa B DNA binding 来源：ChEMBL 靶标：Nuclear factor NF-kappa-B p100 subunit External Id：CHEMBL828644

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incu... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4815371

实验名称：Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incuba... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4815372

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Microhelenin C英文别名

• 11alpha,13-dihydrohelenalintiglinate
• 6-O-Tigloyl-11,13-dihydrohelenalin
• Microhelenin C
• 11,13-Dihydrohelenalin tiglate
• 6-O-Togoloyldihydrohelenalin