甘草异黄酮乙

• 常用名: 甘草异黄酮乙
• 英文名: Licoisoflavone B
• CAS号: 66056-30-2
• 分子量: 352.337
• 密度: 1.4±0.1 g/cm3
• 沸点: 588.9±50.0 °C at 760 mmHg
• 分子式: C₂₀H₁₆O₆
• 熔点: 180-183℃
• 闪点: 215.1±23.6 °C

甘草异黄酮乙用途

Licoisoflavone B,一种异黄酮类化合物,主要来源于 Glycyrrhiza uralensis Fisch.。Licoisoflavone B 抑制脂质过氧化,IC50 为 2.7 μM。

甘草异黄酮乙名称

• 中文名: 甘草异黄酮 B
• 英文名: 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one

甘草异黄酮乙生物活性

• 描述: Licoisoflavone B,一种异黄酮类化合物,主要来源于 Glycyrrhiza uralensis Fisch.。Licoisoflavone B 抑制脂质过氧化,IC50 为 2.7 μM。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Li D, et al. The Application of Ultra-High-Performance Liquid Chromatography Coupled with a LTQ-Orbitrap Mass Technique to Reveal the Dynamic Accumulation of Secondary Metabolites in Licorice under ABA Stress. Molecules. 2017 Oct 20;22(10). pii: E1742.

  [2]. S. Toda, et al. Inhibitory Effects of Isoflavones in Sophora mooracrotiana on Lipid Peroxidation by Superoxide. Pharmaceutical Biology. 2002, 40 (6):422-424.

甘草异黄酮乙物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 588.9±50.0 °C at 760 mmHg
• 熔点: 180-183℃
• 分子式: C₂₀H₁₆O₆
• 分子量: 352.337
• 闪点: 215.1±23.6 °C
• 精确质量: 352.094696
• PSA: 100.13000
• LogP: 5.52
• InChIKey: KIZPADOTOCPASX-UHFFFAOYSA-N
• SMILES: CC1(C)C=Cc2c(ccc(-c3coc4cc(O)cc(O)c4c3=O)c2O)O1
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.683
• 储存条件: 2-8℃，干燥，密闭

甘草异黄酮乙安全信息

• 危害码 (欧洲): Xi
• 海关编码: 2914400090

甘草异黄酮乙海关

• 海关编码: 2914400090
• 中文概述: 2914400090 其他酮醇及酮醛。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

甘草异黄酮乙靶点实验

查看更多实验

实验名称：Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate at 1... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4035961

实验名称：Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4035959

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4035957

实验名称：Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM incubated... 来源：ChEMBL 靶标：Nuclear factor erythroid 2-related factor 2 External Id：CHEMBL4046717

实验名称：Growth inhibition of human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4035954

实验名称：Antifungal activity against Cladosporium cucumerinum CCMI 206 at 100 ug by bioautogra... 来源：ChEMBL 靶标：Cladosporium cucumerinum External Id：CHEMBL1020824

实验名称：Growth inhibition of human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to ... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4035952

实验名称：Growth inhibition of human SW480 cells at 10 uM after 24 hrs by MTS assay relative to... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4035953

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Inhibition of mushroom tyrosinase at 10 uM using L-tyrosine as substrate incubated fo... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL4035963

共10条，当前第1页，共1页

1

甘草异黄酮乙英文别名

• Lico-iso-flavone B
• Licoisoflavone B
• 5,5',7-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one