异鼠李素-3-O-半乳糖苷

• 常用名: 异鼠李素-3-O-半乳糖苷
• 英文名: Isorhamnetin 3-O-galactoside
• CAS号: 6743-92-6
• 分子量: 478.403
• 密度: 1.75±0.1 g/cm3
• 沸点: 834.4±65.0 °C at 760 mmHg
• 分子式: C₂₂H₂₂O₁₂
• 熔点: 267-269 ºC
• 闪点: 291.3±27.8 °C

异鼠李素-3-O-半乳糖苷用途

Isorhamnetin 3-O-galactoside (Cacticin) 是从 Artemisia capillaris Thunberg 中分离出的一种黄酮苷,通过增强抗氧化防御系统和减少炎症信号通路来改善 CCl4-诱导的肝损伤。Isorhamnetin 3-O-galactoside (Cacticin) 具有抗血栓和抗炎作用。

异鼠李素-3-O-半乳糖苷名称

• 中文名: 异鼠李素-3-O-半乳糖苷
• 英文名: Isorhamnetin 3-O-galactoside
• 中文别名: 异鼠李素 3-O-半乳糖苷

异鼠李素-3-O-半乳糖苷生物活性

• 描述: Isorhamnetin 3-O-galactoside (Cacticin) 是从 Artemisia capillaris Thunberg 中分离出的一种黄酮苷,通过增强抗氧化防御系统和减少炎症信号通路来改善 CCl4-诱导的肝损伤。Isorhamnetin 3-O-galactoside (Cacticin) 具有抗血栓和抗炎作用。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Kim DW, et al. Isorhamnetin-3-O-galactoside Protects against CCl4-Induced Hepatic Injury in Mice. Biomol Ther (Seoul). 2012 Jul;20(4):406-12.

  [2]. Kim TH, et al. Anti-inflammatory activities of isorhamnetin-3-O-galactoside against HMGB1-induced inflammatory responses in both HUVECs and CLP-induced septic mice. J Cell Biochem. 2013 Feb;114(2):336-45.

  [3]. Ku SK, et al. Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. Food Chem Toxicol. 2013 Mar;53:197-204.

异鼠李素-3-O-半乳糖苷物理化学性质

• 密度: 1.75±0.1 g/cm3
• 沸点: 834.4±65.0 °C at 760 mmHg
• 熔点: 267-269 ºC
• 分子式: C₂₂H₂₂O₁₂
• 分子量: 478.403
• 闪点: 291.3±27.8 °C
• 精确质量: 478.111115
• PSA: 199.51000
• LogP: 1.71
• InChIKey: CQLRUIIRRZYHHS-HEQLHBKPSA-N
• SMILES: COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2OC2OC(CO)C(O)C(O)C2O)ccc1O
• 蒸汽压: 0.0±3.2 mmHg at 25°C
• 折射率: 1.750
• 储存条件: 2-8°C，密封，干燥
• 水溶解性: Very slightly soluble (0.34 g/L) (25 ºC)

异鼠李素-3-O-半乳糖苷靶点实验

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实验名称：Antioxidant activity assessed as DPPH free radical scavenging activity at 5 uM after ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3862529

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异鼠李素-3-O-半乳糖苷英文别名

• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl β-D-galactopyranoside
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl b-D-glucopyranoside
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl-β-D-glucopyranoside
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl β-D-glucopyranoside
• isorhamnetin 3-glucoside
• Isorhamnetin-3-O-glucoside
• 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on
• Isorhamnetin-3-O-β-D-glucopyranoside
• isohamnetin-3-O-β-glucoside
• 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• 5,7-Dihydroxy-2-(4-hydroxy-3-méthoxyphényl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one
• ISORHAMNETIN-3-GLUCOSIDE