五味子酚

• 常用名: 五味子酚
• 英文名: Schisanhenol
• CAS号: 69363-14-0
• 分子量: 402.481
• 密度: 1.1±0.1 g/cm3
• 沸点: 563.9±50.0 °C at 760 mmHg
• 分子式: C₂₃H₃₀O₆
• 熔点: 130 °C
• 闪点: 294.8±30.1 °C

五味子酚用途

五味子酚(Schisanhenol)是一天然化合物,被报道是UGT2B7的抑制剂。

五味子酚名称

• 中文名: 五味子酚
• 英文名: Schisanhenol
• 中文别名: 去甲去氧五味子素

五味子酚生物活性

• 描述: 五味子酚(Schisanhenol)是一天然化合物,被报道是UGT2B7的抑制剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  天然产物 >> 苯丙酸类
• 参考文献:

  [1]. Song JH, et al. Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis. Phytother Res. 2015 Jun 18.

  [2]. Yu LH, et al. Schisanhenol attenuated ox-LDL-induced apoptosis and reactive oxygen species generation in bovine aorta endothelial cells in vitro. J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):799-806.

  [3]. Wang QY, et al. Schisanhenol derivatives and their biological evaluation against tobacco mosaic virus (TMV). Fitoterapia. 2015 Mar;101:117-24.

  [4]. Xue JY, et al. Antioxidant activity of two dibenzocyclooctene lignans on the aged and ischemic brain in rats. Free Radic Biol Med. 1992;12(2):127-35.

五味子酚物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 563.9±50.0 °C at 760 mmHg
• 熔点: 130 °C
• 分子式: C₂₃H₃₀O₆
• 分子量: 402.481
• 闪点: 294.8±30.1 °C
• 精确质量: 402.204254
• PSA: 66.38000
• LogP: 5.34
• InChIKey: FYSHYFPJBONYCQ-OLZOCXBDSA-N
• SMILES: COc1cc2c(c(O)c1OC)-c1c(cc(OC)c(OC)c1OC)CC(C)C(C)C2
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.536
• 储存条件: 0-10°C;避免加热

五味子酚安全信息

• 海关编码: 2942000000

五味子酚海关

• 海关编码: 2942000000

五味子酚靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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五味子酚英文别名

• (+)-gomisin k3
• HMS2214M09
• (6S,7R)-2,3,10,11,12-Pentamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-1-ol
• UNII:80Y5907NIW