7-溴-5-甲基喹啉-8-醇

• 常用名: 7-溴-5-甲基喹啉-8-醇
• 英文名: Tilbroquinol
• CAS号: 7175-09-9
• 分子量: 238.08100
• 密度: 1.612g/cm3
• 沸点: 342.2ºC at 760 mmHg
• 分子式: C₁₀H₈BrNO
• 熔点: N/A
• 闪点: 160.8ºC

7-溴-5-甲基喹啉-8-醇用途

Tilbroquinol具有抗原生动物活性,可作用于霍乱杆菌。

7-溴-5-甲基喹啉-8-醇名称

• 中文名: 7-溴-5-甲基喹啉-8-醇
• 英文名: 7-bromo-5-methylquinolin-8-ol

7-溴-5-甲基喹啉-8-醇生物活性

• 描述: Tilbroquinol具有抗原生动物活性,可作用于霍乱杆菌。
• 相关类别:
  信号通路 >> 抗感染 >> 寄生物
  研究领域 >> 感染
• 参考文献:

  [1]. Bougoudogo, F, Fournier, J. M.; Dodin, A. "In vitro sensitivity of Vibrio cholerae serotype 0:139 to an intestinal antiseptic tiliquinol-tilbroquinol combination". Bulletin de la Societe de pathologie exotique (1990) 87 (1): 38-40.

  [2]. International Drug Names

7-溴-5-甲基喹啉-8-醇物理化学性质

• 密度: 1.612g/cm3
• 沸点: 342.2ºC at 760 mmHg
• 分子式: C₁₀H₈BrNO
• 分子量: 238.08100
• 闪点: 160.8ºC
• 精确质量: 236.97900
• PSA: 33.12000
• LogP: 3.01130
• InChIKey: JMOVFFLYGIQXMM-UHFFFAOYSA-N
• SMILES: Cc1cc(Br)c(O)c2ncccc12
• 折射率: 1.692
• 储存条件: 2-8℃

7-溴-5-甲基喹啉-8-醇靶点实验

查看更多实验

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029349

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029350

实验名称：Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DIL... 来源：ChEMBL 靶标：Hepatotoxicity External Id：CHEMBL1909321

实验名称：Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum act... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3137722

实验名称：Highest frequency of moderate liver toxicity observed during clinical trials, express... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3137723

实验名称：Acute liver toxicity defined via clinical observations and clear clinical-chemistry r... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137724

实验名称：Highest frequency of acute liver toxicity observed during clinical trials, expressed ... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3137725

实验名称：Cytolytic liver toxicity, either proven histopathologically or where the ratio of max... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137726

实验名称：Choleostatic liver toxicity, either proven histopathologically or where the ratio of ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137727

实验名称：Severe hepatitis, defined as possibly life-threatening liver failure or through clini... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137728

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7-溴-5-甲基喹啉-8-醇英文别名

• Tilbroquinolum [INN-Latin]
• 7-Bromo-5-methyl-8-quinolinol
• 7-bromo-5-methyl-quinolin-8-ol
• 5-Methyl-7-brom-8-hydroxychinolin
• EINECS 230-533-6
• Tilbroquinol (INN)
• Tilbroquinolum
• 8-hydroxy-7-bromo-5-methylquinoline
• tilbroquinol
• 7-bromo-8-hydroxy-5-methylquinoline
• 7-Brom-5-methyl-8-hydroxy-chinolin
• 5-METHYL-7-BROMO-8-HYDROXYQUINOLINE