ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET结构式
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常用名 | ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET | 英文名 | Substance P (free acid) |
|---|---|---|---|---|
| CAS号 | 71977-09-8 | 分子量 | 1348.61000 | |
| 密度 | 1.41 g/cm3 | 沸点 | N/A | |
| 分子式 | C63H97N17O14S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
用途Substance P, Free Acid 是 substance P 的类似物,但是不具有 substance P 的生物活性。 |
| 中文名 | ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET |
|---|---|
| 英文名 | substance p |
| 英文别名 | 更多 |
| 密度 | 1.41 g/cm3 |
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| 分子式 | C63H97N17O14S |
| 分子量 | 1348.61000 |
| 精确质量 | 1347.71000 |
| PSA | 536.14000 |
| LogP | 4.09310 |
| 储存条件 | 2-8℃ |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
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Synthesis of potent antagonists of substance P by modifying the methionyl and glutaminyl residues of its C-terminal hexapeptide and without using D-amino acids.
Int. J. Pept. Protein Res. 41 , 411-414, (1993) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11-NH2 residue is replaced by the alpha, gamma-dimethyl, alpha, gamma-dibenzyl and alpha, gamma-di-tert-butyl esters of glutamic acid. ... |
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Synthesis of peptides by the solid-phase method. 7. Substance P and analogues.
J. Med. Chem. 25 , 64, (1982) Substance P and 21 related peptides containing isosteric or isofunctional groups were prepared by the solid-phase method. After purification by gel filtration and ion-exchange chromatography, the comp... |
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Biological activity of substance P methyl ester.
Mol. Pharmacol. 20 , 457, (1981)
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| H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OH |
| RPKPQQFFGLM |
| H-RPKPQQFFGLM-OH |
| RPKPQQFFGLM-OH |
| [Met-OH11] substance P |
| ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET |
| Substance P, free acid |
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