苄氟噻嗪

• 常用名: 苄氟噻嗪
• 英文名: bendroflumethiazide
• CAS号: 73-48-3
• 分子量: 421.415
• 密度: 1.5±0.1 g/cm3
• 沸点: 602.1±65.0 °C at 760 mmHg
• 分子式: C₁₅H₁₄F₃N₃O₄S₂
• 熔点: 205-207ºC
• 闪点: 318.0±34.3 °C

苄氟噻嗪用途

苯卓氟甲肼是一种口服利尿剂。苯卓氟甲基噻嗪是一种抗高血压药物。苯卓氟甲基噻嗪在动脉性高血压疾病的研究中具有潜力[1]。

苄氟噻嗪名称

• 中文名: 苄氟噻嗪
• 英文名: bendroflumethiazide
• 中文别名: 3-苄基-3,4-二氢-6-(三氟甲基)-2H-1,2,4-苯并噻二嗪-7-磺酰胺-1,1-二氧化物 | 3-苄基-3,二氢-6-(三氟甲基)-2H-1,2,4-苯并噻二嗪-7-氨基磺酰-1,1-二氧化物

苄氟噻嗪生物活性

• 描述: 苯卓氟甲肼是一种口服利尿剂。苯卓氟甲基噻嗪是一种抗高血压药物。苯卓氟甲基噻嗪在动脉性高血压疾病的研究中具有潜力[1]。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. GRIEBLE HG, et al. Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone. Arch Intern Med. 1962;110:26-33.

苄氟噻嗪物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 602.1±65.0 °C at 760 mmHg
• 熔点: 205-207ºC
• 分子式: C₁₅H₁₄F₃N₃O₄S₂
• 分子量: 421.415
• 闪点: 318.0±34.3 °C
• 精确质量: 421.037781
• PSA: 135.12000
• LogP: 2.07
• InChIKey: HDWIHXWEUNVBIY-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc2c(cc1C(F)(F)F)NC(Cc1ccccc1)NS2(=O)=O
• 外观性状: 白色固体
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.584
• 储存条件: 通风低温干燥
• 水溶解性: Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent).

苄氟噻嗪MSDS

苄氟噻嗪MSDS英文版

苄氟噻嗪毒性和生态

苄氟噻嗪安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 2
• RTECS号: DK8225000

苄氟噻嗪靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of TGF-b 来源：NCGC 靶标：Smad3 [Homo sapiens] External Id：SMAD3101

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苄氟噻嗪英文别名

• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide
• Pluryl
• benzoflumethiazide
• 3-Benzyl-6-(trifluorométhyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxyde
• Bendrofluazide
• 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide
• Naturetin
• 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 3-Benzyl-3,4-dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-Dioxide
• 3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Benzydroflumethiazide
• Centyl
• Benzylrodiuran
• Berkozide
• bendroflumethiazide
• bendroflumethazide
• Neo-naclex
• Naturine
• 3-(Phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• bendroflumetazide
• Aprinox
• T66 BSWM EM DHJ D1R& HXFFF ISZW
• Salures