VU0155094

• 常用名: VU0155094
• 英文名: VU0155094
• CAS号: 731006-86-3
• 分子量: 436.523
• 密度: 1.2±0.1 g/cm3
• 沸点: 667.0±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₄N₂O₄S
• 熔点: N/A
• 闪点: 357.2±31.5 °C

VU0155094用途

VU0155094是一种有效的选择性pan III组mGlu阳性变构调节剂,mGlu8/7/4的IC50分别为3.43/1.5/0.93 uM；显示出比I组和II组mGlus(mGlu1/2/3)高30倍的选择性。/5/6)。

VU0155094名称

• 英文名: Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate

VU0155094生物活性

• 描述: VU0155094是一种有效的选择性pan III组mGlu阳性变构调节剂,mGlu8/7/4的IC50分别为3.43/1.5/0.93 uM；显示出比I组和II组mGlus(mGlu1/2/3)高30倍的选择性。/5/6)。
• 参考文献: References 1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. View Related Products by Target mGluR

VU0155094物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 667.0±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₄N₂O₄S
• 分子量: 436.523
• 闪点: 357.2±31.5 °C
• 精确质量: 436.145691
• LogP: 4.87
• InChIKey: BCNKQXDDMIBITO-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(-n2c(C)cc(C(=O)CSc3ccc(NC(C)=O)cc3)c2C)cc1
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.606

VU0155094靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen 来源：NCGC External Id：tdp43-p2-repeat

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

共120条，当前第1页，共12页

1

2

3

4

5

VU0155094英文别名

• Benzoic acid, 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-, methyl ester
• MFCD04625924
• Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate