VU0155094

Modify Date: 2024-02-13 18:01:29

VU0155094 Structure
VU0155094 structure
Common Name VU0155094
CAS Number 731006-86-3 Molecular Weight 436.523
Density 1.2±0.1 g/cm3 Boiling Point 667.0±55.0 °C at 760 mmHg
Molecular Formula C24H24N2O4S Melting Point N/A
MSDS N/A Flash Point 357.2±31.5 °C

 Use of VU0155094


VU0155094 is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively; displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6).

 Names

Name Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate
Synonym More Synonyms

 VU0155094 Biological Activity

Description VU0155094 is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively; displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6).
References References 1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. View Related Products by Target mGluR

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 667.0±55.0 °C at 760 mmHg
Molecular Formula C24H24N2O4S
Molecular Weight 436.523
Flash Point 357.2±31.5 °C
Exact Mass 436.145691
LogP 4.87
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.606

 Synonyms

Benzoic acid, 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-, methyl ester
MFCD04625924
Methyl 4-(3-{[(4-acetamidophenyl)sulfanyl]acetyl}-2,5-dimethyl-1H-pyrrol-1-yl)benzoate