O-去甲基阿司咪唑

• 常用名: O-去甲基阿司咪唑
• 英文名: O-Desmethyl Astemizole
• CAS号: 73736-50-2
• 分子量: 444.54400
• 密度: 1.25g/cm3
• 沸点: 644.2ºC at 760 mmHg
• 分子式: C₂₇H₂₉FN₄O
• 熔点: 92-94ºC
• 闪点: 343.4ºC

O-去甲基阿司咪唑名称

• 中文名: O-去甲基阿司咪唑
• 英文名: 4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol

O-去甲基阿司咪唑物理化学性质

• 密度: 1.25g/cm3
• 沸点: 644.2ºC at 760 mmHg
• 熔点: 92-94ºC
• 分子式: C₂₇H₂₉FN₄O
• 分子量: 444.54400
• 闪点: 343.4ºC
• 精确质量: 444.23300
• PSA: 53.32000
• LogP: 5.05920
• InChIKey: LAGYWHSFHIMTPE-UHFFFAOYSA-N
• SMILES: Oc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1
• 折射率: 1.645

O-去甲基阿司咪唑靶点实验

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实验名称：Inhibition of heme crystallization after 16 hrs 来源：ChEMBL 靶标：Heme External Id：CHEMBL1249739

实验名称：Inhibition of human Potassium channel HERG expressed in mammalian cells 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL766814

实验名称：In vivo antihistaminic activity using compound 48/80 induced lethality test in rat af... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL780746

实验名称：Inhibition of serotonin skin reaction in rat after 2 hr of subcutaneous administratio... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL783284

实验名称：Antimalarial activity against chloroquine-sensitive Plasmodium yoelii 17X infected in... 来源：ChEMBL 靶标：Plasmodium yoelii External Id：CHEMBL1249754

实验名称：Inhibition of human ERG expressed in CHO cells by whole cell patch clamp technique 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL954102

实验名称：Antimalarial activity against chloroquine-sensitive Plasmodium vinckei infected in mi... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1249753

实验名称：In vivo histamine induced lethality after 3 hours of iv administration in guinea pig 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL684813

实验名称：Oral bioavailability in human 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL1249751

实验名称：In vivo histamine induced lethality after 24 hours of iv administration in guinea pig 来源：ChEMBL 靶标：Cavia porcellus External Id：CHEMBL684812

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O-去甲基阿司咪唑英文别名

• O-Desmethyl Astemizole
• DESMETHEYLASTEMIZOLE
• R 44 271
• 1-(4-fluorobenzyl)-N-(1-(4-(2,2,2-trifluoroethoxy)phenylethyl)piperidin-4-yl)-1H-benzo[d]imidazol-2-amine
• Desmethylasteizole
• 4-(2-(4-((1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl)ethyl)phenol
• [14C]-Desmethylastemizole
• O-Demethylastemizole
• Demethylastemizole
• Desmethylastemizole
• 4-<2-<4-<<1-<(4-fluorophenyl)methyl>-1H-benzimidazol-2-yl>amino>-1-piperidinyl>ethyl>phenol