恩氯米芬柠檬酸盐

• 常用名: 恩氯米芬柠檬酸盐
• 英文名: Enclomiphene citrate
• CAS号: 7599-79-3
• 分子量: 598.08300
• 密度: N/A
• 沸点: 509ºC at 760mmHg
• 分子式: C₃₂H₃₆ClNO₈
• 熔点: N/A
• 闪点: 261.6ºC

恩氯米芬柠檬酸盐用途

Enclomiphene citrate 是一种有效、可口服的 oestrogen receptor 拮抗剂,具有抗雌激素作用。

恩氯米芬柠檬酸盐名称

• 中文名: 恩氯米芬柠檬酸盐
• 英文名: 2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanami ne 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• 中文别名: 反式-氯米芬柠檬酸盐

恩氯米芬柠檬酸盐生物活性

• 描述: Enclomiphene citrate 是一种有效、可口服的 oestrogen receptor 拮抗剂,具有抗雌激素作用。
• 相关类别:
  信号通路 >> 其他 >> 雌激素受体/ERR
  研究领域 >> 其他
• 参考文献:

  [1]. Fontenot GK, et al. Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice. BJU Int. 2016 Feb;117(2):344-50.

恩氯米芬柠檬酸盐物理化学性质

• 沸点: 509ºC at 760mmHg
• 分子式: C₃₂H₃₆ClNO₈
• 分子量: 598.08300
• 闪点: 261.6ºC
• 精确质量: 597.21300
• PSA: 144.60000
• LogP: 5.31410
• InChIKey: PYTMYKVIJXPNBD-BTKVJIOYSA-N
• SMILES: CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1.O=C(O)CC(O)(CC(=O)O)C(=O)O
• 储存条件: -20°C，密闭，干燥

恩氯米芬柠檬酸盐靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule modulators of NR3A 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：SBCCG-A1015-NR3A-Primary-Assay

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恩氯米芬柠檬酸盐英文别名

• trans-clomifene citrate
• Enclomiphene citrate