氟甲睾酮结构式
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常用名 | 氟甲睾酮 | 英文名 | Fluoxymesterone |
|---|---|---|---|---|
| CAS号 | 76-43-7 | 分子量 | 336.441 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 474.2±45.0 °C at 760 mmHg | |
| 分子式 | C20H29FO3 | 熔点 | 240 °C | |
| MSDS | N/A | 闪点 | 240.6±28.7 °C | |
| 符号 |
GHS02, GHS07, GHS08 |
信号词 | Danger |
氟甲睾酮用途Fluoxymesterone is an Androgen. The mechanism of action of fluoxymesterone is as an Androgen Receptor Agonist. |
| 中文名 | 氟甲睾酮 |
|---|---|
| 英文名 | Fluoxymesterone |
| 中文别名 | 氟羟甲基睾酮 | 氟羟甲基睾丸素 | 龙坦特伦 |
| 英文别名 | 更多 |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 474.2±45.0 °C at 760 mmHg |
| 熔点 | 240 °C |
| 分子式 | C20H29FO3 |
| 分子量 | 336.441 |
| 闪点 | 240.6±28.7 °C |
| 精确质量 | 336.210083 |
| PSA | 57.53000 |
| LogP | 2.17 |
| 外观性状 | 白色至淡黄色晶体粉末 |
| 蒸汽压 | 0.0±2.7 mmHg at 25°C |
| 折射率 | 1.562 |
| 储存条件 | 密封贮藏，储存在阴凉、干燥地方。 |
| 稳定性 | 与强氧化剂反应。 |
| 水溶解性 | NEGLIGIBLE |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:2 3.氢键受体数量:4 4.可旋转化学键数量:0 5.互变异构体数量:5 6.拓扑分子极性表面积57.5 7.重原子数量:24 8.表面电荷:0 9.复杂度:630 10.同位素原子数量:0 11.确定原子立构中心数量:7 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状：白色无味粉末 2. 密度（g/mL,25℃）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：240 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC,5.2kPa）：未确定 7. 折射率：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º, C=1,乙醇）：104 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,20ºC）：未确定 12. 饱和蒸气压（kPa,20ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：微溶于水 |
| 符号 |
GHS02, GHS07, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H225-H315-H360FD |
| 补充危害声明 | May form explosive peroxides. |
| 警示性声明 | P201-P210-P280-P308 + P313-P370 + P378-P403 + P235 |
| 危害码 (欧洲) | Xn: Harmful; |
| 风险声明 (欧洲) | R63 |
| 安全声明 (欧洲) | S22-S36-S24/25 |
| 危险品运输编码 | UN2252 - class 3 - PG 2 - 1,2-Dimethoxyethane solution |
| WGK德国 | 3 |
| RTECS号 | BV8390000 |
| 海关编码 | 2937290018 |
|
~%
氟甲睾酮 76-43-7 |
| 文献：Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ; |
|
~%
氟甲睾酮 76-43-7 |
| 文献：Journal of the American Chemical Society, , vol. 78, p. 500 US2793218 , ; |
|
~%
氟甲睾酮 76-43-7 |
| 文献：Journal of the American Chemical Society, , vol. 78, p. 500 |
| 氟甲睾酮上游产品 3 | |
|---|---|
| 氟甲睾酮下游产品 1 | |
| 海关编码 | 2937290018 |
|---|
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Rat liver lysosomal and mitochondrial activities are modified by anabolic-androgenic steroids.
Med. Sci Sports Exerc. 31 , 243, (1999) The aim of this study was to examine the separate and combined effects of an 8-wk treatment with high doses of 17alpha-alkylated anabolic-androgenic steroids (AAS) and exercise training on selected ly... |
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Biotransformation of 17-alkyl steroids in the equine: high-performance liquid chromatography-mass spectrometric and gas chromatography-mass spectrometric analysis of fluoxymesterone metabolites in urine samples.
J. Chromatogr. B. Biomed. Sci. Appl. 704 , 119, (1997) In this study the equine metabolism of fluoxymesterone (9alpha-fluoro-11beta-17beta-dihydroxy-17alpha-meth ylandrost-4-ene-3-one) given orally has been investigated. The parent material was not detect... |
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Comparison of chemotherapy with chemohormonal therapy as first-line therapy for metastatic, hormone-sensitive breast cancer: An Eastern Cooperative Oncology Group study.
J. Clin. Oncol. 18(2) , 262-6, (2000) Although hormonal therapy represents standard therapy for metastatic hormone-sensitive disease, many patients receive initial chemotherapy because of the location, bulk, or aggressiveness of their dis... |
| 11b,17b-Dihydroxy-9a-fluoro-17a-methyl-4-androsten-3-one |
| (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
| Testosterone, 9-fluoro-11β-hydroxy-17-methyl- |
| 9a-Fluoro-11b-hydroxy-17a-methyltestosterone |
| MFCD00010480 |
| 9α-Fluoro-11β-hydroxy-17-methyltestosterone |
| (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one |
| Androst-4-en-3-one, 9-fluoro-11β,17β-dihydroxy-17-methyl- |
| Halotestin |
| EINECS 200-961-8 |
| Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11β,17β)- |
| fluoxymesterone |
| (8S,9R,10S,11S,13S,14S,17S)-9-Fluor-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-on |
| (11β,17β)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one |
| (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-triméthyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-3H-cyclopenta[a]phénanthrén-3-one |
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CAS号53649-13-1