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(2Α,6Α)-1,2,3,4,5,6-六氢-6,11-二甲基-3-(2-丙烯基)-2,6-亚甲基-3-喷他佐辛-8-醇

更新时间:2025-08-29 09:44:51

(2Α,6Α)-1,2,3,4,5,6-六氢-6,11-二甲基-3-(2-丙烯基)-2,6-亚甲基-3-喷他佐辛-8-醇结构式
(2Α,6Α)-1,2,3,4,5,6-六氢-6,11-二甲基-3-(2-丙烯基)-2,6-亚甲基-3-喷他佐辛-8-醇结构式
品牌特惠专场
常用名 (2Α,6Α)-1,2,3,4,5,6-六氢-6,11-二甲基-3-(2-丙烯基)-2,6-亚甲基-3-喷他佐辛-8-醇 英文名 SKF-10047
CAS号 7619-35-4 分子量 257.37100
密度 N/A 沸点 N/A
分子式 C17H23NO 熔点 N/A
MSDS 美版 闪点 N/A

 用途


SKF-10047 is a sigma-1 receptor agonist.

 名称

中文名 (2Α,6Α)-1,2,3,4,5,6-六氢-6,11-二甲基-3-(2-丙烯基)-2,6-亚甲基-3-喷他佐辛-8-醇
英文名 (+)-skf-10,047
英文别名 更多

 物理化学性质

分子式 C17H23NO
分子量 257.37100
精确质量 257.17800
PSA 23.47000
LogP 3.04030
InChIKey ZTGMHFIGNYXMJV-BZJVTDFFSA-N
SMILES C=CC[NH+]1CCC2(C)c3cc(O)ccc3CC1C2C.[Cl-]

 安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲) 22-24/25
危险品运输编码 NONH for all modes of transport
WGK德国 3

 文献26

更多文献
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells.

Exp. Eye Res. 107 , 21-31, (2013)

Sigma-1 receptors (σ-1rs) exert neuroprotective effects on retinal ganglion cells (RGCs) both in vivo and in vitro. This receptor has unique properties through its actions on several voltage-gated and...

The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.

Peptides 30 , 2418-2422, (2009)

We previously demonstrated that intracerebroventricular (i.c.v.) administration of the substance P (SP) aminoterminal fragment SP(1-7) attenuates the expression of morphine withdrawal in the male rat....

 靶点实验

查看更多实验

实验名称:Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267247
实验名称:Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267248
实验名称:Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267249
实验名称:Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267250
实验名称:Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green a...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267251
实验名称:Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267245
实验名称:Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green ...
来源:ChEMBL
靶标:Plasmodium falciparum
External Id:CHEMBL1267246
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 英文别名

(+)-N-allyl-N-normetazocine
(+)-N-allylnormetazocine
N-allylnormetazocine
(+)-SKF-10047
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