(R)-(+)- 8-羟基-DPAT氢溴酸盐结构式
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常用名 | (R)-(+)- 8-羟基-DPAT氢溴酸盐 | 英文名 | R(+)-8-Hydroxy DPAT HBr |
|---|---|---|---|---|
| CAS号 | 78095-19-9 | 分子量 | 328.28800 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C16H26BrNO | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
| 中文名 | (R)-(+)-8-羟基-DPAT氢溴酸盐(8-羟基 DPAT) |
|---|---|
| 英文名 | (7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol,hydrobromide |
| 英文别名 | 更多 |
| 分子式 | C16H26BrNO |
|---|---|
| 分子量 | 328.28800 |
| 精确质量 | 327.12000 |
| PSA | 23.47000 |
| LogP | 4.32960 |
| InChIKey | BATPBOZTBNNDLN-PFEQFJNWSA-N |
| SMILES | Br.CCCN(CCC)C1CCc2cccc(O)c2C1 |
| 储存条件 | 2-8°C,密封,干燥 |
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Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Oncotarget 6(6) , 3932-46, (2015) HER2-positive breast tumors are associated with a high risk of brain relapse. HER3 is thought to be an indispensible signaling substrate for HER2 (encoded by ERBB2) and is induced in breast cancer-bra... |
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Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats.
Behav. Brain Res. 243 , 97-101, (2013) Antisocial aggressive behavior in adolescents represents growing clinical and social problem. Previously the implication of 5-HT1A receptor in the regulation of fear-induced aggression was shown. Here... |
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Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.
Neurochem. Int. 61(8) , 1344-56, (2012) This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT... |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1266185
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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实验名称:Dicer-mediated maturation of pre-microRNA
来源:Center for Chemical Genomics, University of Michigan
靶标:N/A
External Id:TargetID_659_CEMA
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| C16H25NO.HBr |