氟马西尼杂质F

更新时间：2025-08-25 20:14:18

氟马西尼杂质F结构式	常用名	氟马西尼杂质F	英文名	Flumazenil Impurity F
	CAS号	78756-33-9	分子量	319.74300
	密度	1.43g/cm3	沸点	554ºC at 760 mmHg
	分子式	C₁₅H₁₄ClN₃O₃	熔点	N/A
	MSDS	N/A	闪点	288.9ºC

中文名	8-氯-5,6-二氢-5-甲基-6-氧代-4H-咪唑并[1,5-a][1,4]苯并二氮杂卓-3-羧酸乙酯
英文名	Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]b enzodiazepine-3-carboxylate
中文别名	氟马西尼杂质F
英文别名	更多

密度	1.43g/cm3
沸点	554ºC at 760 mmHg
分子式	C₁₅H₁₄ClN₃O₃
分子量	319.74300
闪点	288.9ºC
精确质量	319.07200
PSA	64.43000
LogP	2.22590
InChIKey	QORLMYYHZLDYOR-UHFFFAOYSA-N
SMILES	CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(Cl)ccc1-2
折射率	1.658

异氰基乙酸乙酯

2999-46-4

~46%

氟马西尼杂质F

78756-33-9

文献：WiSys Technology Foundation, Inc. Patent: US2006/258643 A1, 2006 ; Location in patent: Page/Page column 31-32 ; US 20060258643 A1

异氰基乙酸乙酯

2999-46-4

叔丁醇钾

865-47-4

氯磷酸二乙酯

814-49-3

7-chloro-4-meth...

5973-29-5

详细

文献：Hoffman-La Roche Inc. Patent: US4316839 A1, 1982 ;

异氰基乙酸乙酯

2999-46-4

未登录

1027918-09-7

氟马西尼杂质F

78756-33-9

文献：Yang, Jie; Teng, Yun; Ara, Shamim; Rallapalli, Sundari; Cook, James M. Synthesis, 2009 , # 6 art. no. M05108SS, p. 1036 - 1040

7-chloro-4-meth...

5973-29-5

氟马西尼杂质F

78756-33-9

文献：Gu, Zi-Qiang; Wong, Garry; Dominguez, Celia; Costa, Brian R. de; Rice, Kenner C.; Skolnick, Phil Journal of Medicinal Chemistry, 1993 , vol. 36, # 8 p. 1001 - 1006

异氰基乙酸乙酯

2999-46-4

7-chloro-4-meth...

5973-29-5

氟马西尼杂质F

78756-33-9

文献：Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

氟马西尼杂质F上游产品 4
CAS号2999-46-4 异氰基乙酸乙酯 CAS号865-47-4 叔丁醇钾 CAS号814-49-3 氯磷酸二乙酯 CAS号5973-29-5 7-chloro-4-meth...
氟马西尼杂质F下游产品 0

实验名称：GABA shift ratio at Diazepam sensitive fraction of GABA-A benzodiazepine receptor
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit alpha-3
External Id：CHEMBL841639

实验名称：Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha...
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit alpha-2
External Id：CHEMBL681248

实验名称：Binding affinity against Diazepam sensitive (DS) Gamma-aminobutyric acid A receptor i...
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit alpha-3
External Id：CHEMBL680655

实验名称：Binding affinity against Diazepam insensitive (DI) Gamma-aminobutyric acid A receptor
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit alpha-3
External Id：CHEMBL680654

实验名称：It is the ratio of Ki value for alpha-1-beta-3-gamma-2 to that of alpha-5-beta-3-gamm...
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit gamma-2
External Id：CHEMBL822166

实验名称：Binding affinity against alpha-1-beta-3-gamma-2 GABAA/BzR receptor subtype.
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit gamma-2
External Id：CHEMBL822165

实验名称：Selectivity ratio of alpha1 beta-3 gamma2 GABA A / BzR and alpha5 beta-3 gamma2 GABA ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL847928

实验名称：Selectivity for Diazepam insensitive compared to sensitive GABA-A benzodiazepine rece...
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit alpha-3
External Id：CHEMBL848574

实验名称：Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alph...
来源：ChEMBL
靶标：Gamma-aminobutyric acid receptor subunit gamma-2
External Id：CHEMBL682251

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Ethyl 8-chloro-1-ethyl-4-oxo-4H-quinolizine-3-carboxylate

ethyl 8-chloro-1-ethyl-4H-quinolizin-4-one-3-carboxylate

Flumazenil Impurity F