氯苯达诺

• 常用名: 氯苯达诺
• 英文名: clofedanol
• CAS号: 791-35-5
• 分子量: 289.80000
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₂₀ClNO
• 熔点: 120°
• 闪点: N/A

氯苯达诺用途

氯苯二酚是一种口服有效镇咳剂。氯苯二酚可用于研究上呼吸道感染引起的急性咳嗽[1][2]。

氯苯达诺名称

• 中文名: 氯苯达诺
• 英文名: 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol

氯苯达诺生物活性

• 描述: 氯苯二酚是一种口服有效镇咳剂。氯苯二酚可用于研究上呼吸道感染引起的急性咳嗽[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Boyd EM, et al. Chlophedianol Hydrochloride: A New Antitussive Agent. Can Med Assoc J. 1960 Dec 17;83(25):1298-301.

  [2]. Paul IM. Therapeutic options for acute cough due to upper respiratory infections in children. Lung. 2012 Feb;190(1):41-4.

氯苯达诺物理化学性质

• 熔点: 120°
• 分子式: C₁₇H₂₀ClNO
• 分子量: 289.80000
• 精确质量: 289.12300
• PSA: 23.47000
• LogP: 3.52760
• InChIKey: WRCHFMBCVFFYEQ-UHFFFAOYSA-N
• SMILES: CN(C)CCC(O)(c1ccccc1)c1ccccc1Cl
• 计算化学:

  1.疏水参数计算参考值（XlogP）:3.6

  2.氢键供体数量:1

  3.氢键受体数量:2

  4.可旋转化学键数量:5

  5.互变异构体数量:无

  6.拓扑分子极性表面积:23.5

  7.重原子数量:20

  8.表面电荷:0

  9.复杂度:291

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

氯苯达诺毒性和生态

氯苯达诺靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint... 来源：Broad Institute 靶标：N/A External Id：2084-01_Activator_SinglePoint_HTS_Activity

实验名称：Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberc... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：GDH-TPI_INH_ABS_1536_1X%INH CSRUN

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

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氯苯达诺英文别名

• 3-Dimethylamino-1-phenyl-1-<1-chlor-phenyl>-propanol-(1)
• Clofedanolum
• DL-1-Phenyl-1-(2-chlor-phenyl)-3-dimethylamino-propanol-(1)
• Clophedianol base
• 1-(2-Chlor-phenyl)-3-dimethylamino-1-phenyl-propan-1-ol
• Ulo base
• Chlofedanol
• Dencyl
• Clofedano
• Tussistop
• chlophedianol
• chlophedianol hydrochloride
• Clofedanol
• Calmotusin