苦瓜皂苷 K

• 常用名: 苦瓜皂苷 K
• 英文名: Momordicoside K
• CAS号: 81348-84-7
• 分子量: 648.86700
• 密度: 1.21±0.1 g/cm3
• 沸点: 743.1±60.0 °C at 760 mmHg
• 分子式: C₃₇H₆₀O₉
• 熔点: N/A
• 闪点: N/A

苦瓜皂苷 K用途

苦瓜苷K是一种葫芦烷三萜类化合物[1]。

苦瓜皂苷 K名称

• 中文名: 苦瓜皂苷 K
• 英文名: momordicoside K

苦瓜皂苷 K生物活性

• 描述: 苦瓜苷K是一种葫芦烷三萜类化合物[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 体外研究: 苦瓜甙K需要较高的用量 (>50µg/mL)诱导 ~40%的HNC公司细胞 (Cal27、JHU029、JHU022)死亡[1]。
• 参考文献:

  [1]. Subhayan Sur, et al. Momordicine-I, a Bitter Melon Bioactive Metabolite, Displays Anti-Tumor Activity in Head and Neck Cancer Involving c-Met and Downstream Signaling. Cancers (Basel). 2021 Mar 21;13(6):1432.

苦瓜皂苷 K物理化学性质

• 密度: 1.21±0.1 g/cm3
• 沸点: 743.1±60.0 °C at 760 mmHg
• 分子式: C₃₇H₆₀O₉
• 分子量: 648.86700
• 精确质量: 648.42400
• PSA: 145.91000
• LogP: 3.93390
• InChIKey: HPSVQEWDZSDXRG-ZMMZJDKESA-N
• SMILES: COC(C)(C)C=CCC(C)C1CCC2(C)C3C(OC4OC(CO)C(O)C(O)C4O)C=C4C(CCC(O)C4(C)C)C3(C=O)CCC12C
• 外观性状: 粉末
• 储存条件: 2-8°C， 密封， 干燥， 避光

苦瓜皂苷 K靶点实验

查看更多实验

实验名称：Inhibition of alpha-amylase (unknown origin) assessed as reduction in conversion of s... 来源：ChEMBL 靶标：Alpha-amylase 1A External Id：CHEMBL4402785

实验名称：Inhibition of Saccharomyces cerevisiae alpha-glucosidase at 1.3 mM pre-incubated for ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4402787

实验名称：Fluorescence Mpro inhibition assay (S1) from Article : "Open science discovery of pot... 来源：BindingDB 靶标：N/A External Id：BindingDB_11549_3

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in IL-1beta ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4402790

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in Cox2 mRNA... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4402791

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in iNOS mRNA... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4402792

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in NFkappaB ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4402793

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in IL6 mRNA ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4402794

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苦瓜皂苷 K英文别名

• MFCD21364046