11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

• 常用名: 11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
• 英文名: 11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
• CAS号: 82408-04-6
• 分子量: 363.41000
• 密度: 1.31g/cm3
• 沸点: 565.5ºC at 760 mmHg
• 分子式: C₂₁H₂₁N₃O₃
• 熔点: N/A
• 闪点: 295.8ºC

用途

抗氧化剂-7(SD-7)是一种具有抗氧化活性的苯二氮卓衍生物,其IC50值为470 nM,可清除DPPH(2,2-二苯基-1-苦酰肼基)自由基[1]。

名称

• 英文名: 9,9-dimethyl-6-(4-nitrophenyl)-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one

生物活性

• 描述: 抗氧化剂-7(SD-7)是一种具有抗氧化活性的苯二氮卓衍生物,其IC50值为470 nM,可清除DPPH(2,2-二苯基-1-苦酰肼基)自由基[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Bhagat K, et al. Microwave-assisted synthesis of 11-substituted-3,3-dimethyl-2,3,4,5,10,11-hexahydrodibenzo[b,e][1,4]diazepin-1-one derivatives catalysed by silica supported fluoroboric acid as potent antioxidant and anxiolytic agents. Med Chem Res 28, 2200–2217 (2019).

物理化学性质

• 密度: 1.31g/cm3
• 沸点: 565.5ºC at 760 mmHg
• 分子式: C₂₁H₂₁N₃O₃
• 分子量: 363.41000
• 闪点: 295.8ºC
• 精确质量: 363.15800
• PSA: 86.95000
• LogP: 5.61590
• InChIKey: UGGUUWQHYLAINX-UHFFFAOYSA-N
• SMILES: CC1(C)CC(=O)C2=C(C1)Nc1ccccc1NC2c1ccc([N+](=O)[O-])cc1
• 折射率: 1.658
• 储存条件: -20°C

靶点实验

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英文别名

• MFCD00731281