11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Modify Date: 2025-08-29 11:29:08

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure
11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one structure
Common Name 11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
CAS Number 82408-04-6 Molecular Weight 363.41000
Density 1.31g/cm3 Boiling Point 565.5ºC at 760 mmHg
Molecular Formula C21H21N3O3 Melting Point N/A
MSDS N/A Flash Point 295.8ºC

 Use of 11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one


Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical[1].

 Names

Name 9,9-dimethyl-6-(4-nitrophenyl)-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
Synonym More Synonyms

  Biological Activity

Description Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical[1].
Related Catalog
References

[1]. Bhagat K, et al. Microwave-assisted synthesis of 11-substituted-3,3-dimethyl-2,3,4,5,10,11-hexahydrodibenzo[b,e][1,4]diazepin-1-one derivatives catalysed by silica supported fluoroboric acid as potent antioxidant and anxiolytic agents. Med Chem Res 28, 2200–2217 (2019).

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 565.5ºC at 760 mmHg
Molecular Formula C21H21N3O3
Molecular Weight 363.41000
Flash Point 295.8ºC
Exact Mass 363.15800
PSA 86.95000
LogP 5.61590
Index of Refraction 1.658
Storage condition -20°C

 Synthetic Route

~81%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Kolos; Yurchenko; Orlov; Shishkina; Shishkin Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 12 p. 1550 - 1559

~%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Kolos; Yurchenko; Orlov; Shishkina; Shishkin Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 12 p. 1550 - 1559

~%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Kolos; Yurchenko; Orlov; Shishkina; Shishkin Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 12 p. 1550 - 1559

~%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Eynde, J. -J. Vanden; Mayence, A.; Maquestiau, A.; Anders E. Bulletin des Societes Chimiques Belges, 1992 , vol. 101, # 9 p. 801 - 806

~%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Eynde, J. -J. Vanden; Mayence, A.; Maquestiau, A.; Anders E. Bulletin des Societes Chimiques Belges, 1992 , vol. 101, # 9 p. 801 - 806

~%

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one Structure

11-(4-(Hydroxy(...

CAS#:82408-04-6

Literature: Kolos; Yurchenko; Orlov; Shishkina; Shishkin Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 12 p. 1550 - 1559

 Synonyms

MFCD00731281
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.