3-[(2-乙酰氧基)乙基氨基羰基]吡啶结构式
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常用名 | 3-[(2-乙酰氧基)乙基氨基羰基]吡啶 | 英文名 | SG 209 |
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| CAS号 | 83440-03-3 | 分子量 | 208.21400 | |
| 密度 | 1.182g/cm3 | 沸点 | 430.7ºC at 760 mmHg | |
| 分子式 | C10H12N2O3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 214.3ºC |
3-[(2-乙酰氧基)乙基氨基羰基]吡啶用途SG-209 is a potassium channel opener. |
| 中文名 | 3-[(2-乙酰氧基)乙基氨基羰基]吡啶 |
|---|---|
| 英文名 | SG 209,N-[2-(Acetoxy)ethyl]-3-pyridinecarboxamide |
| 英文别名 | 更多 |
| 密度 | 1.182g/cm3 |
|---|---|
| 沸点 | 430.7ºC at 760 mmHg |
| 分子式 | C10H12N2O3 |
| 分子量 | 208.21400 |
| 闪点 | 214.3ºC |
| 精确质量 | 208.08500 |
| PSA | 68.29000 |
| LogP | 0.76540 |
| InChIKey | JQICNNKLTFYSLS-UHFFFAOYSA-N |
| SMILES | CC(=O)OCCNC(=O)c1cccnc1 |
| 外观性状 | 固体 |
| 折射率 | 1.521 |
| 储存条件 | -20°C, 密封, 干燥 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 安全声明 (欧洲) | 22-24/25 |
| 危险品运输编码 | NONH for all modes of transport |
| 海关编码 | 2933399090 |
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3-[(2-乙酰氧基)乙基氨基羰基]吡啶 83440-03-3 |
| 文献:TERNANSKY, Robert Patent: WO2007/38772 A1, 2007 ; Location in patent: Example 2 ; WO 2007/038772 A1 |
| 3-[(2-乙酰氧基)乙基氨基羰基]吡啶上游产品 2 | |
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| 3-[(2-乙酰氧基)乙基氨基羰基]吡啶下游产品 0 | |
| 海关编码 | 2933399090 |
|---|---|
| 中文概述 | 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo.
J. Pharmacol. Exp. Ther. 354 , 79-87, (2015) Intense research is conducted to identify new molecular mechanisms of angiogenesis. Previous studies have shown that the angiogenic effects of hydrogen sulfide (H2S) depend on the activation of ATP-se... |
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Nicorandil inhibits degranulation and TNF-alpha release from RBL-2H3 cells.
Inflamm. Res. 51 , 176-181, (2002) Nicorandil is a potassium channel opener and nitric oxide (NO) donor, and the hypothesis was tested that these modes of action may inhibit cellular degranulation and release of tumour necrosis factor-... |
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A further study of the vasodilator and negative inotropic mechanisms of action of nicorandil and its congeners in the canine heart.
Cardiovasc. Drugs Ther. 8 , 227-234, (1994) The vasodilator and negative inotropic mechanisms of action of nicorandil and its congeners (SG-209, SG-103, and SG-86) were investigated in isolated canine papillary muscle preparations cross-circula... |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
来源:NCGC
靶标:N/A
External Id:SERCaMPGLuc-p1-antagonist
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:N/A
External Id:HMS1315
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
来源:23265
External Id:IucA Pilot Assay Tocris Library
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| sg 209 |