Helioxanthin 8-1

• 常用名: Helioxanthin 8-1
• 英文名: Helioxanthin 8-1
• CAS号: 840529-13-7
• 分子量: 376.319
• 密度: 1.5±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₀H₁₂N₂O₆
• 熔点: N/A
• 闪点: N/A

Helioxanthin 8-1用途

Helioxanthin 8-1是helioxanthin类似物,具有抗HBV/HCV/HSV-1/HIV的活性,EC50分别为>5/10/1.4/15 uM。

Helioxanthin 8-1名称

• 中文名: Helioxanthin 8-1
• 英文名: 1,3-Benzodioxolo[4,5-g]phthalazine-7,10-dione, 11-(1,3-benzodioxol-5-yl)-8,9-dihydro

Helioxanthin 8-1生物活性

• 描述: Helioxanthin 8-1是helioxanthin类似物,具有抗HBV/HCV/HSV-1/HIV的活性,EC50分别为>5/10/1.4/15 uM。
• 相关类别:
  信号通路 >> 抗感染 >> HBV
  研究领域 >> 感染
• 参考文献:

  [1]. Yeo H, et al. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27;48(2):534-46.

  [2]. Ying C, et al. Helioxanthin analogue 8-1 inhibits duck hepatitis B virus replication in cell culture. Antivir Chem Chemother. 2010;21(2):97-103.

Helioxanthin 8-1物理化学性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₂₀H₁₂N₂O₆
• 分子量: 376.319
• 精确质量: 376.069550
• PSA: 102.64000
• LogP: 3.29
• InChIKey: PXSPEYYAEFFUMN-UHFFFAOYSA-N
• SMILES: O=c1[nH][nH]c(=O)c2c(-c3ccc4c(c3)OCO4)c3c4c(ccc3cc12)OCO4
• 折射率: 1.715
• 储存条件: 2-8℃

Helioxanthin 8-1靶点实验

查看更多实验

实验名称：Decrease in binding of HBV promoter preC/C-EnhII to human HNF4-1 in HepG2(2.2.15) cel... 来源：ChEMBL 靶标：N/A External Id：CHEMBL952497

实验名称：Antiviral activity against Hepatitis B virus 来源：ChEMBL 靶标：Hepatitis B virus External Id：CHEMBL3124245

实验名称：Inhibition of CMV promoter in human HepG2(2.2.15) cells by luciferase reporter gene a... 来源：ChEMBL 靶标：Cytomegalovirus External Id：CHEMBL952496

实验名称：Effect on virus RNA stability on doxycyclin-induced HBV pre genomic RNA production in... 来源：ChEMBL 靶标：Hepatitis B virus External Id：CHEMBL952491

实验名称：Percent inhibition against Hepatitis C virus replication in a cell culture model 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL826432

实验名称：Effect on HBV viral core protein degradation on cyclohexamide terminated cellular pro... 来源：ChEMBL 靶标：Hepatitis B virus External Id：CHEMBL952493

实验名称：Decrease in binding of HBV promoter preC/C-EnhII to HNF3 in human HepG2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL952503

实验名称：Decrease in binding of HBV promoter preC/C-EnhII to HNF4-2 in human HepG2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL952502

实验名称：Down regulation of HNH4-alpha in human HepG2(2.2.15) cells expressing HBV at 0.3 uM b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL937887

实验名称：Decrease in binding of HBV promoter preC/C-EnhII to FTF2 in human HepG2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL952504

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Helioxanthin 8-1英文别名

• Helioxanthin 8-1
• 11-(1,3-Benzodioxol-5-yl)-8,9-dihydro[1,3]benzodioxolo[4,5-g]phthalazine-7,10-dione