Gsk299115a

• 常用名: Gsk299115a
• 英文名: Gsk299115a
• CAS号: 864082-35-9
• 分子量: 415.27
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₆Cl₂N₄O₂
• 熔点: N/A
• 闪点: N/A

Gsk299115a用途

GSK299115A是一种G蛋白偶联受体激酶(GRK)和PKA抑制剂[1]。

Gsk299115a名称

• 英文名: GSK299115A

Gsk299115a生物活性

• 描述: GSK299115A是一种G蛋白偶联受体激酶(GRK)和PKA抑制剂[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 蛋白酪氨酸激酶 >> PKA
  信号通路 >> 干细胞及 Wnt 通路 >> PKA
• 参考文献:

  [1]. Homan KT, et al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem Biol. 2015 Jan 16;10(1):310-9.

Gsk299115a物理化学性质

• 分子式: C₂₀H₁₆Cl₂N₄O₂
• 分子量: 415.27
• InChIKey: RHTXWIKPNGROHZ-UHFFFAOYSA-N
• SMILES: CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(Cl)c(Cl)c2)CC(=O)N1

Gsk299115a靶点实验

查看更多实验

实验名称：GSK_PKIS: KIT (T670I mutant) mean inhibition at 1 uM [Nanosyn] 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL1962129

实验名称：GSK_PKIS: KIT (T670I mutant) mean inhibition at 0.1 uM [Nanosyn] 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL1962128

实验名称：ROCK 1 Kinase Activity Assay from Article 10.1021/jm0609014: "Development of dihydrop... 来源：BindingDB 靶标：N/A External Id：BindingDB_1776_1

实验名称：GSK_PKIS: KIT (V560G mutant) mean inhibition at 1 uM [Nanosyn] 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL1962131

实验名称：GSK_PKIS: KIT (V560G mutant) mean inhibition at 0.1 uM [Nanosyn] 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL1962130

实验名称：GSK_PKIS: LCK mean inhibition at 1 uM [Nanosyn] 来源：ChEMBL 靶标：Tyrosine-protein kinase Lck External Id：CHEMBL1962133

实验名称：GSK_PKIS: LCK mean inhibition at 0.1 uM [Nanosyn] 来源：ChEMBL 靶标：Tyrosine-protein kinase Lck External Id：CHEMBL1962132

实验名称：GSK_PKIS: LTK mean inhibition at 1 uM [Nanosyn] 来源：ChEMBL 靶标：Leukocyte tyrosine kinase receptor External Id：CHEMBL1962135

实验名称：GSK_PKIS: LTK mean inhibition at 0.1 uM [Nanosyn] 来源：ChEMBL 靶标：Leukocyte tyrosine kinase receptor External Id：CHEMBL1962134

实验名称：GSK_PKIS: JAK3 mean inhibition at 1 uM [Nanosyn] 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK3 External Id：CHEMBL1962121

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