3-(4-imidazol-1-ylphenyl)-4-methyl-1H-pyridazin-6-one

• 常用名: 3-(4-imidazol-1-ylphenyl)-4-methyl-1H-pyridazin-6-one
• 英文名: 3-(4-imidazol-1-ylphenyl)-4-methyl-1H-pyridazin-6-one
• CAS号: 86798-76-7
• 分子量: 252.27100
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₂N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(4-imidazol-1-ylphenyl)-4-methyl-1H-pyridazin-6-one

物理化学性质

• 分子式: C₁₄H₁₂N₄O
• 分子量: 252.27100
• 精确质量: 252.10100
• PSA: 63.83000
• LogP: 2.34330
• InChIKey: JHCQIYAUCIHYNU-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)[nH]nc1-c1ccc(-n2ccnc2)cc1

靶点实验

查看更多实验

实验名称：Ratio of IC50 values for PDE III and PDE I. 来源：ChEMBL 靶标：N/A External Id：CHEMBL844591

实验名称：Ratio of IC50 values for PDE III and PDE II. 来源：ChEMBL 靶标：N/A External Id：CHEMBL844592

实验名称：Inhibitory concentration against cGMP PDE I enzyme in guinea pig 来源：ChEMBL 靶标：Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B External Id：CHEMBL765554

实验名称：Inhibition of cGMP PDE II enzyme in guinea pig at 1E-5M concentration 来源：ChEMBL 靶标：cGMP-dependent 3',5'-cyclic phosphodiesterase External Id：CHEMBL759146

实验名称：Inhibitory concentration against cAMP PDE I enzyme in guinea pig 来源：ChEMBL 靶标：Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B External Id：CHEMBL765553

实验名称：Inhibition of cGMP PDE II enzyme in guinea pig at 1E-4M concentration 来源：ChEMBL 靶标：cGMP-dependent 3',5'-cyclic phosphodiesterase External Id：CHEMBL759145

实验名称：50% increase in myocardial contractility (dP/dt max) in anesthetized dogs on intraven... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL667242

实验名称：Inhibitory concentration against cAMP PDE II enzyme in guinea pig 来源：ChEMBL 靶标：cGMP-dependent 3',5'-cyclic phosphodiesterase External Id：CHEMBL759151

实验名称：Inhibition of cAMP PDE II enzyme 来源：ChEMBL 靶标：cGMP-dependent 3',5'-cyclic phosphodiesterase External Id：CHEMBL765556

实验名称：Inhibition of cGMP PDE II enzyme 来源：ChEMBL 靶标：cGMP-dependent 3',5'-cyclic phosphodiesterase External Id：CHEMBL765557

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英文别名

• 6-[4-(1H-imidazol-1-yl)phenyl]-5-methyl-3(2H)-pyridazinone