S6K1-IN-DG2

• 常用名: S6K1-IN-DG2
• 英文名: S6K1-IN-DG2
• CAS号: 871340-88-4
• 分子量: 389.25
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₇BrN₆O
• 熔点: N/A
• 闪点: N/A

S6K1-IN-DG2用途

S6K1-IN-DG2(化合物66)是p70S6K抑制剂(IC50:<100nM)[1]。

S6K1-IN-DG2名称

• 英文名: 3-Bromo-4-[4-(2-methoxyphenyl)-1-piperazinyl]-1H-pyrazolo[3,4-d]p yrimidine

S6K1-IN-DG2生物活性

• 描述: S6K1-IN-DG2(化合物66)是p70S6K抑制剂(IC50:<100nM)[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> MAPK/ERK信号通路 >> 核糖体S6激酶(RSK)
• 参考文献:

  [1]. Neel K. Anand, et al. Kinase modulators and methods of use. Patent. WO2005117909.

S6K1-IN-DG2物理化学性质

• 分子式: C₁₆H₁₇BrN₆O
• 分子量: 389.25
• 精确质量: 388.06500
• PSA: 70.17000
• LogP: 2.58060
• InChIKey: CQXAPCMYRSTDGK-UHFFFAOYSA-N
• SMILES: COc1ccccc1N1CCN(c2ncnc3n[nH]c(Br)c23)CC1

S6K1-IN-DG2靶点实验

查看更多实验

实验名称：Inhibition of FGR at 1 uM in presence of 10 uM ATP by Select Screen kinase assay rela... 来源：ChEMBL 靶标：Tyrosine-protein kinase Fgr External Id：CHEMBL1252422

实验名称：Inhibition of FGFR4 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay re... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 4 External Id：CHEMBL1252421

实验名称：Inhibition of FGFR3 K650E mutant at 1 uM in presence of 10 uM ATP by Select Screen ki... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL1252420

实验名称：Inhibition of FGFR3 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay re... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL1252419

实验名称：Inhibition of FGFR2 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay re... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 2 External Id：CHEMBL1252418

实验名称：Inhibition of FGFR1 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay re... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 1 External Id：CHEMBL1252417

实验名称：Inhibition of FES at 1 uM in presence of 10 uM ATP by Select Screen kinase assay rela... 来源：ChEMBL 靶标：Tyrosine-protein kinase Fes/Fps External Id：CHEMBL1252416

实验名称：Inhibition of FER at 1 uM in presence of 10 uM ATP by Select Screen kinase assay rela... 来源：ChEMBL 靶标：Tyrosine-protein kinase Fer External Id：CHEMBL1252415

实验名称：Inhibition of GRK5 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay rel... 来源：ChEMBL 靶标：G protein-coupled receptor kinase 5 External Id：CHEMBL1252430

实验名称：Inhibition of GRK4 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay rel... 来源：ChEMBL 靶标：G protein-coupled receptor kinase 4 External Id：CHEMBL1252429

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