2-((4-(4-(pyridin-4-yl)-1H-pyrazol-5-yl)phenoxy)methyl)quinoline

• 常用名: 2-((4-(4-(pyridin-4-yl)-1H-pyrazol-5-yl)phenoxy)methyl)quinoline
• 英文名: 2-((4-(4-(pyridin-4-yl)-1H-pyrazol-5-yl)phenoxy)methyl)quinoline
• CAS号: 871507-11-8
• 分子量: 378.42600
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₁₈N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-((4-(4-(pyridin-4-yl)-1H-pyrazol-5-yl)phenoxy)methyl)quinoline

物理化学性质

• 分子式: C₂₄H₁₈N₄O
• 分子量: 378.42600
• 精确质量: 378.14800
• PSA: 63.69000
• LogP: 5.26590
• InChIKey: VRWJZGHUCOFGPZ-UHFFFAOYSA-N
• SMILES: c1ccc2nc(COc3ccc(-c4[nH]ncc4-c4ccncc4)cc3)ccc2c1

靶点实验

查看更多实验

实验名称：Inhibition of rat recombinant PDE10A transfected in Sf9 cells 来源：ChEMBL 靶标：cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A External Id：CHEMBL1051662

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301368

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Behavioral effect in sc dosed mouse assessed as conditioned avoidance response after ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1051666

实验名称：PDE Enzyme Inhibition Assay from Article 10.1021/jm900521k: "Discovery of a Novel Cla... 来源：BindingDB 靶标：N/A External Id：BindingDB_3342_1

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301365

实验名称：Ratio of drug level in brain to plasma in mouse 来源：ChEMBL 靶标：N/A External Id：CHEMBL1051667

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301367

实验名称：Increase in cGMP level in mouse striatum at 10 mg/kg, sc 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1051665

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301366

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英文别名

• AMG 0074
• 2-[4-(4-pyridin-4-yl-2H-pyrazol-3-yl)-phenoxymethyl]-quinoline
• 2-[-4-(4-Pyridin-4-yl-2H-pyrazol-3-yl)-phenoxymethyl]-quinoline