Mardepodect

• 常用名: Mardepodect
• 英文名: PF-2545920
• CAS号: 898562-94-2
• 分子量: 392.453
• 密度: 1.2±0.1 g/cm3
• 沸点: 568.6±50.0 °C at 760 mmHg
• 分子式: C₂₅H₂₀N₄O
• 熔点: N/A
• 闪点: 297.7±30.1 °C

Mardepodect名称

• 中文名: 2-[[4-[1-甲基-4-(4-吡啶基)-1H-吡唑-3-基]苯氧基]甲基]-喹啉
• 英文名: Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]
• 中文别名: 2-[(4-(1-甲基-4-(吡啶-4-基)-1H-吡唑-3-基)苯氧基)甲基]喹啉

Mardepodect生物活性

• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 磷酸二酯酶(PDE)
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Verhoest PR, et al. Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia. J Med Chem, 2009, 52(16), 5188-5196.

  [2]. Grauer SM, et al. Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia. J Pharmacol Exp Ther, 2009, 331(2), 574-590.

Mardepodect物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 568.6±50.0 °C at 760 mmHg
• 分子式: C₂₅H₂₀N₄O
• 分子量: 392.453
• 闪点: 297.7±30.1 °C
• 精确质量: 392.163696
• PSA: 52.83000
• LogP: 3.52
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.661
• 储存条件: -20°C，密闭，干燥

Mardepodect安全信息

• 海关编码: 2933990090

Mardepodect海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Mardepodect英文别名

• 2-({4-[1-Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)chinolin
• 2-({4-[1-Methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline
• 2-{4-[1-methyl-4-(pyridin-4-yl)pyrazol-3-yl]phenoxymethyl}quinoline
• 2-{4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxymethyl}quinoline
• UNII:R9Y8EY0G42
• Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-
• 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline
• 2-[(4-(1-Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl]quinoline
• MP 10
• PF-2545920