7-溴-3,4-二氢-2H-异喹啉-1-酮

更新时间：2025-08-22 13:28:16

7-溴-3,4-二氢-2H-异喹啉-1-酮结构式	常用名	7-溴-3,4-二氢-2H-异喹啉-1-酮	英文名	7-Bromo-3,4-dihydro-1(2H)-isoquinolinone
	CAS号	891782-60-8	分子量	226.070
	密度	1.6±0.1 g/cm3	沸点	438.4±45.0 °C at 760 mmHg
	分子式	C₉H₈BrNO	熔点	N/A
	MSDS	美版	闪点	219.0±28.7 °C

中文名	7-溴-3,4-二氢-2H-异喹啉-1-酮
英文名	7-bromo-3,4-dihydro-2h-isoquinolin-1-one
中文别名	-溴-3,4-二氢-2H-异喹啉-1-酮
英文别名	更多

密度	1.6±0.1 g/cm3
沸点	438.4±45.0 °C at 760 mmHg
分子式	C₉H₈BrNO
分子量	226.070
闪点	219.0±28.7 °C
精确质量	224.978912
PSA	29.10000
LogP	1.81
InChIKey	DRDDOAWCDDBYHZ-UHFFFAOYSA-N
SMILES	O=C1NCCc2ccc(Br)cc21
蒸汽压	0.0±1.1 mmHg at 25°C
折射率	1.600
储存条件	室温

危害码 (欧洲)	Xi
海关编码	2933790090

7-氨基-3,4-二氢异喹啉-...

66491-03-0

~64%

7-溴-3,4-二氢-2H-异...

891782-60-8

文献：GLAXO GROUP LIMITED Patent: WO2007/122258 A1, 2007 ; Location in patent: Page/Page column 76 ;

6-溴茚酮

14548-39-1

~59%

7-溴-3,4-二氢-2H-异...

891782-60-8

文献：Bristol-Myers Squibb Company Patent: US2010/160303 A1, 2010 ; Location in patent: Page/Page column 36 ; US 20100160303 A1

methyl 4-(bromo...

305447-65-8

~93%

7-溴-3,4-二氢-2H-异...

891782-60-8

文献：Spicer, Julie A.; Lena, Gersande; Lyons, Dani M.; Huttunen, Kristiina M.; Miller, Christian K.; O'Connor, Patrick D.; Bull, Matthew; Helsby, Nuala; Jamieson, Stephen M. F.; Denny, William A.; Ciccone, Annette; Browne, Kylie A.; Lopez, Jamie A.; Rudd-Schmidt, Jesse; Voskoboinik, Ilia; Trapani, Joseph A. Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9542 - 9555

4-溴苯乙胺

73918-56-6

7-溴-3,4-二氢-2H-异...

891782-60-8

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 14 p. 4255 - 4258

7-溴-3,4-二氢-2H-异喹啉-1-酮上游产品 3
CAS号66491-03-0 7-氨基-3,4-二氢异喹啉-... CAS号14548-39-1 6-溴茚酮 CAS号73918-56-6 4-溴苯乙胺
7-溴-3,4-二氢-2H-异喹啉-1-酮下游产品 1
CAS号1231892-74-2 7-(4,4,5,5-四甲基-...

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

实验名称：Inhibition of PARP1 (unknown origin) by fluorescence analysis
来源：ChEMBL
靶标：Poly [ADP-ribose] polymerase 1
External Id：CHEMBL3631406

实验名称：Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluoresc...
来源：ChEMBL
靶标：Protein mono-ADP-ribosyltransferase PARP10
External Id：CHEMBL3631405

实验名称：Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK...
来源：ChEMBL
靶标：Protein mono-ADP-ribosyltransferase PARP10
External Id：CHEMBL3631404

实验名称：Inhibition of GFP-tagged wild-type PARP-10 (unknown origin) expressed in HEK-293T cel...
来源：ChEMBL
靶标：Protein mono-ADP-ribosyltransferase PARP10
External Id：CHEMBL3631540

实验名称：Inhibition of GFP-tagged PARP-10 L926G mutant (unknown origin) expressed in HEK-293T ...
来源：ChEMBL
靶标：Protein mono-ADP-ribosyltransferase PARP10
External Id：CHEMBL3631539

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7-bromo-1,2,3,4-tetrahydroisoquinolin-1-one

7-Bromo-3,4-dihydroisoquinolin-1(2H)-one

7-Bromo-3,4-dihydro-1(2H)-isoquinolinone