EAAT2 activator 1

• 常用名: EAAT2 activator 1
• 英文名: EAAT2 activator 1
• CAS号: 892415-28-0
• 分子量: 331.80
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₁ClFN₃S
• 熔点: N/A
• 闪点: N/A

EAAT2 activator 1用途

EAAT2激活剂1是兴奋性氨基酸转运体2(EAAT2)的有效激活剂。EAAT2是主要的谷氨酸转运体,其功能是清除突触中的谷氨酸。EAAT2激活剂1剂量依赖性地增加EAAT2蛋白水平[1]。

EAAT2 activator 1名称

• 英文名: EAAT2 activator 1

EAAT2 activator 1生物活性

• 描述: EAAT2激活剂1是兴奋性氨基酸转运体2(EAAT2)的有效激活剂。EAAT2是主要的谷氨酸转运体,其功能是清除突触中的谷氨酸。EAAT2激活剂1剂量依赖性地增加EAAT2蛋白水平[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> EAAT2
  研究领域 >> 神经疾病
• 靶点实验:

  EAAT2[1]

• 参考文献:

  [1]. Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011;21(19):5774-5777.

EAAT2 activator 1物理化学性质

• 分子式: C₁₆H₁₁ClFN₃S
• 分子量: 331.80
• InChIKey: DCLFFJASADCESO-UHFFFAOYSA-N
• SMILES: Fc1cccc(Cl)c1CSc1ccc(-c2ccccn2)nn1

EAAT2 activator 1靶点实验

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实验名称：Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 24 hrs by Wes... 来源：ChEMBL 靶标：Astrocyte External Id：CHEMBL1838753

实验名称：qHTS assay for inhibitors of human lactate dehydrogenase 来源：NCGC 靶标：N/A External Id：LDHA

实验名称：Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 4 hrs by West... 来源：ChEMBL 靶标：Astrocyte External Id：CHEMBL1838944

实验名称：Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ... 来源：NCGC External Id：stopgo-p2-SytraCBC-dual-FF

实验名称：Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ... 来源：NCGC External Id：stopgo-p2-SytraCBC-dual-Ren

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

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