脱氢尼群地平结构式
|
常用名 | 脱氢尼群地平 | 英文名 | Dehydronitrendipine |
|---|---|---|---|---|
| CAS号 | 89267-41-4 | 分子量 | 358.345 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 465.4±45.0 °C at 760 mmHg | |
| 分子式 | C18H18N2O6 | 熔点 | 59-61℃ | |
| MSDS | N/A | 闪点 | 235.3±28.7 °C |
| 中文名 | 2,6-二甲基-4-(3-硝基苯基)-吡啶-3,5-二羧酸-3-乙酯-5-甲酯 |
|---|---|
| 英文名 | 3-O-ethyl 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate |
| 中文别名 | 尼群地平杂质 A |
| 英文别名 | 更多 |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 465.4±45.0 °C at 760 mmHg |
| 熔点 | 59-61℃ |
| 分子式 | C18H18N2O6 |
| 分子量 | 358.345 |
| 闪点 | 235.3±28.7 °C |
| 精确质量 | 358.116486 |
| PSA | 111.31000 |
| LogP | 3.56 |
| InChIKey | YEHVABIPGJLMET-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1cccc([N+](=O)[O-])c1 |
| 蒸汽压 | 0.0±1.1 mmHg at 25°C |
| 折射率 | 1.569 |
|
~99%
脱氢尼群地平 89267-41-4 |
| 文献:Pfister Synthesis, 1990 , # 8 p. 689 - 690 |
| 脱氢尼群地平上游产品 1 | |
|---|---|
| 脱氢尼群地平下游产品 0 | |
|
Pharmacokinetics of nitrendipine in patients with renal failure: comparison to normal subjects.
J. Cardiovasc. Pharmacol. 6 Suppl 7 , S974-6, (1984) To determine the effect of decreased renal function on the elimination kinetics of the calcium entry blocker nitrendipine and its metabolite, we gave 18 subjects with various levels of renal dysfuncti... |
| Nitrendipine M (dehydro) |
| Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate |
| 2,6-dimethyl-3-methoxycarbonyl-4-(m-nitrophenyl)-5-ethoxycarbonylpyridine |
| 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester |
| (+/-)-Oxidized Nitrendipine |
| Bay-m 4786 |
| 2,6-Dimethyl-4-(3-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-ethyl; ester 5-methyl ester |
| 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester |
| Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate |
| 3-ethyl 5-methyl 4-(3-nitrophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylate |
| 3,5-Pyridinedicarboxylic acid,2,6-dimethyl-4-(3-nitrophenyl)-,ethyl methyl ester |
| ethylmethyl-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate |