叔-O-甲基白当归素

• 常用名: 叔-O-甲基白当归素
• 英文名: t-OMe-Byakangelicin
• CAS号: 89560-97-4
• 分子量: 348.35
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₀O₇
• 熔点: N/A
• 闪点: N/A

叔-O-甲基白当归素用途

(R) -叔OMe byakangelicin是一种呋喃香豆素,对肝脏药物代谢酶(DME)活性具有抑制作用。(R) 从当归未成熟果实中可分离到赤霉素叔OMe[1][2]。

叔-O-甲基白当归素名称

• 中文名: 叔-O-甲基白当归素
• 英文名: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2-hydroxy-3-methoxy-3-methylbutoxy]-4-methoxy

叔-O-甲基白当归素生物活性

• 描述: (R) -叔OMe byakangelicin是一种呋喃香豆素,对肝脏药物代谢酶(DME)活性具有抑制作用。(R) 从当归未成熟果实中可分离到赤霉素叔OMe[1][2]。
• 相关类别:
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Mendez J, et al. Furocoumarins from Angelica pachycarpa. Phytochemistry, 1983, 22(11): 2599-2601.

  [2]. Shin K H, et al. Effect of the constituents of Angelicae dahuricae radix on hepatic drug metabolizing enzyme activity[J]. Korean Journal of Pharmacognosy, 1988, 19(1): 19-27.

叔-O-甲基白当归素物理化学性质

• 分子式: C₁₈H₂₀O₇
• 分子量: 348.35
• InChIKey: SCGNAXSXMSFZME-GFCCVEGCSA-N
• SMILES: COc1c2ccoc2c(OCC(O)C(C)(C)OC)c2oc(=O)ccc12
• 储存条件: 2-8℃

叔-O-甲基白当归素靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

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叔-O-甲基白当归素英文别名

• t-OMe-Byakangelicin