生长激素结构式
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常用名 | 生长激素 | 英文名 | Somatotropin |
|---|---|---|---|---|
| CAS号 | 9002-72-6 | 分子量 | 154.120 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 410.7±35.0 °C at 760 mmHg | |
| 分子式 | C7H6O4 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 216.3±22.4 °C |
生长激素用途垂体性侏儒症及早应用GH可使生长速度显著改善，但不促进性早熟，故需在适当时机，并用性激素。 |
| 中文名 | 生长激素 |
|---|---|
| 英文名 | Somatotropin |
| 英文别名 | 更多 |
| 密度 | 1.6±0.1 g/cm3 |
|---|---|
| 沸点 | 410.7±35.0 °C at 760 mmHg |
| 分子式 | C7H6O4 |
| 分子量 | 154.120 |
| 闪点 | 216.3±22.4 °C |
| 精确质量 | 154.026611 |
| LogP | 1.16 |
| 外观性状 | lyophilized powder |
| 蒸汽压 | 0.0±1.0 mmHg at 25°C |
| 折射率 | 1.671 |
| 储存条件 | 2-8°C |
| 稳定性 | 本品由人、牛、羊的脑下垂体前叶抽提而得。人生长激素(HGH)是人垂体前叶分泌的一种多肽激素，由垂体嗜酸细胞分泌。它是由191个氨基酸组成的单一多肽链，带有两个双硫氢，等电点pH＝5.5。HGH相当稳定，其活性在冰冻条件可保持数年，在室温放置48h无变化。不同种属动物生长激素肽链的长度相近，但氨基酸排列顺序差别很大，所以其他动物的生长激素对人无促进生长的作用。 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| 危害码 (欧洲) | B |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
| RTECS号 | TO7385000 |
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Actions of NPY, and its Y1 and Y2 receptors on pulsatile growth hormone secretion during the fed and fasted state.
J. Neurosci. 34(49) , 16309-19, (2014) The hypothalamic NPY system plays an important role in regulating food intake and energy expenditure. Different biological actions of NPY are assigned to NPY receptor subtypes. Recent studies demonstr... |
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Neonatal estrogen exposure results in biphasic age-dependent effects on the skeletal development of male mice.
Endocrinology 156(1) , 193-202, (2015) Peak bone mass, one of the most important predictors for fracture risk later in life, is attained during puberty and adolescence and influenced by neonatal and pubertal sex-specific gonadal hormones a... |
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Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131.
Life Sci. 109(1) , 20-9, (2014) The 28 amino acid hormone ghrelin, the natural ligand for the growth hormone secretagogue, or ghrelin receptor (GHR), has diverse physiological functions, including a possible role as a gastrointestin... |
| EINECS 202-760-0 |
| 3,4-Dihydroxybenzoic acid |
| Benzoic acid, 3,4-dihydroxy- |
| protocatechuic acid |
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