CeMMEC2

• 常用名: CeMMEC2
• 英文名: CeMMEC2
• CAS号: 902955-25-3
• 分子量: 257.334
• 密度: 1.3±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₄H₁₉N₅
• 熔点: N/A
• 闪点: N/A

CeMMEC2用途

CeMMEC2是一种新型有效的BRD4抑制剂,IC50为0.9 uM,与BRD4的两个溴结构域结合,与(S)-JQ1相当。

CeMMEC2名称

• 英文名: N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine

CeMMEC2生物活性

• 描述: CeMMEC2是一种新型有效的BRD4抑制剂,IC50为0.9 uM,与BRD4的两个溴结构域结合,与(S)-JQ1相当。
• 参考文献: References 1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10. 2. Blank, J. et al. WPO patent WO/2014/191894 (2014). View Related Products by Target Bromodomain

CeMMEC2物理化学性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₁₄H₁₉N₅
• 分子量: 257.334
• 精确质量: 257.164032
• LogP: 2.41
• InChIKey: NCACTGQDGOLTBA-UHFFFAOYSA-N
• SMILES: Cc1nnc2ccc(NCCC3=CCCCC3)nn12
• 折射率: 1.673

CeMMEC2靶点实验

查看更多实验

实验名称：Identification of CBX7 inhibitors - Primary Alpha Screen 来源：15290 靶标：N/A External Id：CBX7-Alpha-primary

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS1303

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：A screen for compounds that inhibit viral RNA polymerase binding and polymerization a... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Chain A, Poliovirus Polymerase With Gtp External Id：HMS750

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CeMMEC2英文别名

• N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine