CeMMEC2

Modify Date: 2024-01-26 09:56:56

CeMMEC2 Structure
CeMMEC2 structure
Common Name CeMMEC2
CAS Number 902955-25-3 Molecular Weight 257.334
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C14H19N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CeMMEC2


CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.

 Names

Name N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine
Synonym More Synonyms

 CeMMEC2 Biological Activity

Description CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.
References References 1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10. 2. Blank, J. et al. WPO patent WO/2014/191894 (2014). View Related Products by Target Bromodomain

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C14H19N5
Molecular Weight 257.334
Exact Mass 257.164032
LogP 2.41
Index of Refraction 1.673

 Synonyms

1,2,4-Triazolo[4,3-b]pyridazin-6-amine, N-[2-(1-cyclohexen-1-yl)ethyl]-3-methyl-
N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine