Cyclopentenyl uracil

• 常用名: Cyclopentenyl uracil
• 英文名: Cyclopentenyl uracil
• CAS号: 90597-20-9
• 分子量: 240.21300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₀H₁₂N₂O₅
• 熔点: N/A
• 闪点: N/A

Cyclopentenyl uracil用途

环戊烯基尿嘧啶是尿苷激酶的一种非细胞毒性抑制剂,可有效阻止宿主和完整小鼠肿瘤组织挽救循环尿苷[1]。

Cyclopentenyl uracil名称

• 英文名: 1-((1R,2S,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl)-2,4-(1H,3H)-pyrimidinedione

Cyclopentenyl uracil生物活性

• 描述: 环戊烯基尿嘧啶是尿苷激酶的一种非细胞毒性抑制剂,可有效阻止宿主和完整小鼠肿瘤组织挽救循环尿苷[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Cysyk RL, et al. Cyclopentenyl uracil: an effective inhibitor of uridine salvage in vivo. Biochem Pharmacol. 1995;49(2):203-207.

Cyclopentenyl uracil物理化学性质

• 分子式: C₁₀H₁₂N₂O₅
• 分子量: 240.21300
• 精确质量: 240.07500
• PSA: 115.55000
• InChIKey: FCWVOJUKQSHZIV-VDAHYXPESA-N
• SMILES: O=c1ccn(C2C=C(CO)C(O)C2O)c(=O)[nH]1
• 外观性状: 固体
• 储存条件: 2-8°C，密封，干燥

Cyclopentenyl uracil靶点实验

查看更多实验

实验名称：Compound was tested for its ability to inhibit L1210 cell growth after 72 hr at 500 u... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL878108

实验名称：Compound was tested for its ability to inhibit L1210 cell growth after 72 hr at 100 u... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL701049

实验名称：Inhibition of uridine kinase from L1210 cells was evaluated by measuring the retentio... 来源：ChEMBL 靶标：Uridine-cytidine kinase 1 External Id：CHEMBL816761

实验名称：Inhibition of uridine kinase from L1210 cells was evaluated by measuring the retentio... 来源：ChEMBL 靶标：Uridine-cytidine kinase 1 External Id：CHEMBL816760

实验名称：In vitro antiviral activity against HIV-1 in human PBM cells. 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL757786

实验名称：In vitro cytotoxicity in vero cells. 来源：ChEMBL 靶标：Vero External Id：CHEMBL820965

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：In vitro antiviral activity against West Nile Virus. 来源：ChEMBL 靶标：West Nile virus External Id：CHEMBL819957

实验名称：In vitro cytotoxicity in CEM cells. 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL656048

实验名称：NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L... 来源：DTP/NCI 靶标：N/A External Id：MCF7_OneDose

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Cyclopentenyl uracil英文别名

• (1'R,2'S,3'R)-1-[2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil
• 1-((1R,2S,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl)-2,4-(1H,3H)-pyrimidinedione