2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one

• 常用名: 2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one
• 英文名: 2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one
• CAS号: 942425-25-4
• 分子量: 257.29
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₅N₅O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one

物理化学性质

• 分子式: C₁₃H₁₅N₅O
• 分子量: 257.29
• InChIKey: UKWYEWZXFXMQQC-UHFFFAOYSA-N
• SMILES: CCC1CNC(=O)c2cc(-c3ccnc(N)n3)[nH]c21

靶点实验

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实验名称：Half life in nu/nu mouse at 10 mg/kg, po administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019798

实验名称：Oral bioavailability in nu/nu mouse at 10 mg/kg administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019799

实验名称：Tmax in nu/nu mouse at 10 mg/kg, po administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019796

实验名称：AUC (0 to infinity) in nu/nu mouse at 10 mg/kg, po administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019797

实验名称：Inhibition of CDK9 来源：ChEMBL 靶标：Cyclin-dependent kinase 9 External Id：CHEMBL1019786

实验名称：Antiproliferative activity against human A2780 cells after 72 hrs by luciferase based... 来源：ChEMBL 靶标：A2780 External Id：CHEMBL1019872

实验名称：In Vitro Kinase Assay from Article 10.1021/jm800977q: "First Cdc7 kinase inhibitors: ... 来源：BindingDB 靶标：N/A External Id：BindingDB_3054_1

实验名称：Inhibition of human Cdc7 assessed as inhibition of rate of phosphorylation of Mcm2 pr... 来源：ChEMBL 靶标：Cell division cycle 7-related protein kinase External Id：CHEMBL1019871

实验名称：Half life in nu/nu mouse at 10 mg/kg, iv administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019794

实验名称：Clearance in nu/nu mouse at 10 mg/kg, iv administered as single dose 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1019792

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