2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one

Name: Half life in nu/nu mouse at 10 mg/kg, po administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019798

Name: Oral bioavailability in nu/nu mouse at 10 mg/kg administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019799

Name: Tmax in nu/nu mouse at 10 mg/kg, po administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019796

Name: AUC (0 to infinity) in nu/nu mouse at 10 mg/kg, po administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019797

Name: Inhibition of CDK9
Source: ChEMBL
Target: Cyclin-dependent kinase 9
External Id: CHEMBL1019786

Name: Antiproliferative activity against human A2780 cells after 72 hrs by luciferase based...
Source: ChEMBL
Target: A2780
External Id: CHEMBL1019872

Name: In Vitro Kinase Assay from Article 10.1021/jm800977q: "First Cdc7 kinase inhibitors: ...
Source: BindingDB
Target: N/A
External Id: BindingDB_3054_1

Name: Inhibition of human Cdc7 assessed as inhibition of rate of phosphorylation of Mcm2 pr...
Source: ChEMBL
Target: Cell division cycle 7-related protein kinase
External Id: CHEMBL1019871

Name: Half life in nu/nu mouse at 10 mg/kg, iv administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019794

Name: Clearance in nu/nu mouse at 10 mg/kg, iv administered as single dose
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL1019792