(2Z)-1-(1-吡咯烷基)-3-(3,4,5-三甲氧基苯基)-2-丙烯-1-酮

• 常用名: (2Z)-1-(1-吡咯烷基)-3-(3,4,5-三甲氧基苯基)-2-丙烯-1-酮
• 英文名: Piperlotine D
• CAS号: 958296-13-4
• 分子量: 291.34
• 密度: 1.2±0.1 g/cm3
• 沸点: 482.8±45.0 °C at 760 mmHg
• 分子式: C₁₆H₂₁NO₄
• 熔点: N/A
• 闪点: 245.8±28.7 °C

用途

哌罗汀D是一种抗血小板聚集剂。Piperlotine D可以从具有抗血小板聚集活性的Piper lolot中提取。哌罗汀D抑制花生四烯酸诱导的血小板聚集,IC50为43.4μg/mL[1]。

名称

• 中文名: (2Z)-1-(1-吡咯烷基)-3-(3,4,5-三甲氧基苯基)-2-丙烯-1-酮
• 英文名: Piperlotine D

生物活性

• 描述: 哌罗汀D是一种抗血小板聚集剂。Piperlotine D可以从具有抗血小板聚集活性的Piper lolot中提取。哌罗汀D抑制花生四烯酸诱导的血小板聚集,IC50为43.4μg/mL[1]。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Li CY, et al. Isolation and identification of antiplatelet aggregatory principles from the leaves of Piper lolot. J Agric Food Chem. 2007 Nov 14;55(23):9436-42.

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 482.8±45.0 °C at 760 mmHg
• 分子式: C₁₆H₂₁NO₄
• 分子量: 291.34
• 闪点: 245.8±28.7 °C
• 精确质量: 291.147064
• PSA: 48.00000
• LogP: 1.76
• InChIKey: TYFKYDTUEMTUNY-SREVYHEPSA-N
• SMILES: COc1cc(C=CC(=O)N2CCCC2)cc(OC)c1OC
• 外观性状: 油状物体
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.565
• 储存条件: 2-8℃，干燥，密闭

安全信息

• 危害码 (欧洲): Xi

靶点实验

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英文别名

• (2Z)-1-(1-Pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one